Results 71 to 80 of about 369,559 (294)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Scale dependences of local form non-Gaussianity parameters from a DBI isocurvature field
, 2011 We derive the spectral indices and their runnings of local form $f_{NL}$ and $g_{NL}$ from a DBI isocurvature field and we find that the indices are suppressed by the sound speed $c_s$.
Huang, Qing-Guo, Lin, Chunshan
core +1 more source
Near-infrared spectroscopic indices for unresolved stellar populations: I. Template galaxy spectra [PDF]
, 2018 Context. A new generation of spectral synthesis models has been developed in recent years, but there is no matching set of template galaxy spectra, in terms of quality and resolution, for testing and refining the new models.
Cesetti, M. +7 more
core +4 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Scientific African, 2020 The difference in structure and composition of landcover types requires accurate mapping of burned areas for post-fire ecological assessments. Spectral indices for burned area mapping are mostly hard-coded to particular environments.
Kudzai Shaun Mpakairi +2 more
doaj +1 more source
Dirac Operators on Quantum Weighted Projective Spaces
, 2015 The quantum weighted projective algebras $\mathbb{C}[\mathbb{WP}_{k,l,q}]$ are coinvariant subalgebras of the quantum group algebra $\mathbb{C}[SU_{q,2}]$. For each pair of indices $k,l$, two $2$-summable spectral triples will be constructed.
Harju, Antti J.
core +1 more source
Is the Universe More Transparent to Gamma Rays Than Previously Thought? [PDF]
, 2008 The MAGIC collaboration has recently reported the detection of the strong gamma-ray blazar 3C279 during a 1-2 day flare. They have used their spectral observations to draw conclusions regarding upper limits on the opacity of the Universe to high energy ...
Scully, Sean T., Stecker, Floyd W.
core +3 more sources
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
An Informed and Systematic Method to Identify Variable Mid-L Dwarfs
The Astrophysical JournalMost brown dwarfs show some level of photometric or spectral variability. However, finding the most variable dwarfs more suited for a thorough variability monitoring campaign remained a challenge until a few years ago with the design of spectral indices ...
Natalia Oliveros-Gomez +5 more
doaj +1 more source