Results 231 to 240 of about 5,686,377 (385)

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

A comparison of the hard ASCA spectral slopes of broad- and narrow-line Seyfert 1 galaxies [PDF]

, 1997
W. N. Brandt, Smita Mathur, M. Elvis
openalex   +1 more source

Thin-film lithium niobate terahertz differential field detectors with a bandwidth reaching 3 terahertz. [PDF]

Nat Commun
Herter A, Shams-Ansari A, Lončar M, Faist J.   +3 more
europepmc   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

A Comprehensive Spectral and Variability Study of Narrow‐Line Seyfert 1 Galaxies Observed by ASCA . I. Observations and Time Series Analysis [PDF]

, 1999
Karen M. Leighly
openalex   +1 more source

Single-photon dual-comb ghost imaging spectroscopy. [PDF]

Nat Commun
Peng D, Mei L, Gong Z, Zuo Z, Liu Z, Di Y, Liu X, Gu C, Li W, Yan G.   +9 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

The application of Monte Carlo methods to the synthesis of spectral line profiles arising from accretion disc winds [PDF]

, 1995
C. Knigge, J. A. Woods, J. E. Drew
openalex   +1 more source

Raman-based PAT for multi-attribute monitoring during VLP recovery by dual-stage CFF: attribute-specific spectral preprocessing for model transfer. [PDF]

Front Bioeng Biotechnol
Dietrich A, Heim L, Hubbuch J.
europepmc   +1 more source

Optimized Cell‐Based Platform for Platelet‐Free Detection of Heparin‐Induced Thrombocytopenia Antibodies

Advanced Biology, EarlyView.
This study optimized a cell‐based ELISA for HIT antibody detection using PF4‐coated breast cancer cells (MDA‐MB‐231). Enhanced binding was observed at 50 mM NaCl and 4% paraformaldehyde fixation. Live MDA‐MB‐231 and HCT‐116 cells demontrated superior sensitivity and specificity, providing a promising platelet‐free alternative for clinical HIT diagnosis.
Li‐Yu Chen, Uwe Schirmer, Peter F. Zipfel, Doris Heinrich, Thi‐Huong Nguyen   +4 more
wiley   +1 more source