Results 131 to 140 of about 7,706,107 (291)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

On-line tool wear identification by tribo emf signal analysis [PDF]

, 1993
The acoustic air-borne signal, the cutting tool vibration, and the stochastic component of the tribo emf signal produced by single point continuous turning operations have been analysed using statistical techniques.
Donovan, Alan
core  

Investigation on Experimental Conditions and Quantitative Analysis for Fe and Si Elements in General Aluminum by Laser Induced Breakdown Spectroscopy Technique

, 2019
In order to promote the application of LIBS technology in electrolytic aluminum industry, give full play to its advantages of rapidness, no preparation and multi-element simultaneous detection.
Cong Zhi-bo, Sun Lan-xiang, Lu Hui, Hu Xiao-jun, Cao Bin, Dong Wei   +5 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Fast Z transformation for system identification

, 1974
: Time series analysis -- Spectral analysis -- Fast Fourier transform -- On-line systems identification -- Digital signal processing -- Z and Laplace ...
Corinthios, Michael J.
core   +1 more source

The intelligent fault identification method based on multi-source information fusion and deep learning

Scientific Reports
Faults represent significant geological structures. Conventional fault identification methods pri-marily rely on the linear features of faults, achieved through the interpretation of remote sensing imagery (RSI).
Dashu Guo, Xiaoshuang Yang, Peng Peng, Lei Zhu, Handong He   +4 more
doaj   +1 more source

Spectral image analysis for measuring ripeness of tomatoes [PDF]

, 2002
In this study, spectral images of five ripeness stages of tomatoes have been recorded and analyzed. The electromagnetic spectrum between 396 and 736 nm was recorded in 257 bands (every 1.3 nm).
Young, I.T., Heijden, G.W.A.M., van der, Polder, G.   +2 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

An Intelligent Passive System for UAV Detection and Identification in Complex Electromagnetic Environments via Deep Learning

Drones
With the rapid proliferation of unmanned aerial vehicles (UAVs) and the associated rise in security concerns, there is a growing demand for robust detection and identification systems capable of operating reliably in complex electromagnetic environments.
Guyue Zhu, Cesar Briso, Yuanjian Liu, Zhipeng Lin, Kai Mao, Shuangde Li, Yunhong He, Qiuming Zhu   +7 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source