Results 31 to 40 of about 1,565,423 (283)
Spectrally adapted physics-informed neural networks for solving unbounded domain problems
Solving analytically intractable partial differential equations (PDEs) that involve at least one variable defined on an unbounded domain arises in numerous physical applications.
Mingtao Xia, Lucas Böttcher, Tom Chou
doaj +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
The computational performance and accuracy of a parallel pseudo-spectral solver is assessed, and the solver is validated for direct numerical simulations (DNS) of bypass transition and turbulent boundary layer flows.
S. Bhushan, S. Muthu
doaj +1 more source
Fast and Accurate Computation of Vertical Modes
The vertical modes of linearized equations of motion are widely used by the oceanographic community in numerous theoretical and observational contexts.
Jeffrey J. Early +2 more
doaj +1 more source
Effectiveness of Floating-Point Precision on the Numerical Approximation by Spectral Methods
With the fast advances in computational sciences, there is a need for more accurate computations, especially in large-scale solutions of differential problems and long-term simulations. Amid the many numerical approaches to solving differential problems,
José A. O. Matos, Paulo B. Vasconcelos
doaj +1 more source
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Generalized Qualification and Qualification Levels for Spectral Regularization Methods [PDF]
The concept of qualification for spectral regularization methods for inverse ill-posed problems is strongly associated to the optimal order of convergence of the regularization error. In this article, the definition of qualification is extended and three
A. Neubauer +14 more
core +2 more sources
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter +17 more
wiley +1 more source

