Results 61 to 70 of about 254,314 (265)

Nonlinear unmixing of minerals based on the log and continuum removal model

European Journal of Remote Sensing, 2019
Spectral mixing models for minerals can be complex, and choosing the right unmixing model is indispensable to ensure the accuracy of spectral unmixing. Continuum removal (CR) and natural log operation have the potential to eliminate nonlinear effects in ...
Hengqian Zhao, Xuesheng Zhao
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Spectral Regularization for Diffusion Models

CoRR
Diffusion models are typically trained using pointwise reconstruction objectives that are agnostic to the spectral and multi-scale structure of natural signals. We propose a loss-level spectral regularization framework that augments standard diffusion training with differentiable Fourier- and wavelet-domain losses, without modifying the diffusion ...
Satish Chandran, Nícolas Roque dos Santos, Yunshu Wu, Greg Ver Steeg, Evangelos Papalexakis   +4 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Spectral Ripples in Normal and Electric Hearing Models

Technologies
Devising a psychophysical test to assess spectral resolution has not been easy. Two tests that have been used previously are the spectral ripple test and the spectral-temporally modulated ripple test (SMRT).
Savine S. M. Martens, Jeroen J. Briaire, Johan H. M. Frijns   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Real-space spectral simulation of quantum spin models: Application to generalized Kitaev models

SciPost Physics Core
The proliferation of quantum fluctuations and long-range entanglement presents an outstanding challenge for the numerical simulation of interacting spin systems with exotic ground states. Here, we present a toolset of Chebyshev polynomial-based iterative
Francisco M. O. Brito, Aires Ferreira
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Spectral Models for Subsidy Allocation in Industrial Systems

AppliedMath
This paper studies subsidy allocation in interconnected industrial systems using the spectral theory of positive matrices. The allocation is characterized by the Perron eigenvector of a cost matrix describing inter-factory interactions.
Gorenc Mateja
doaj   +1 more source