Results 71 to 80 of about 254,576 (265)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Study on Outdoor Spectral Inversion of Winter Jujube Based on BPDF Models
AgricultureThe outdoor spectral detection of winter jujube quality is affected by complex ambient light and surface heterogeneity, resulting in limited inversion accuracy.
Yabei Di +5 more
doaj +1 more source
Solution of the voter model by spectral analysis
Physical Review E, 2015 An exact spectral analysis of the Markov Propagator for the Voter model is presented for the complete graph, and extended to the complete bipartite graph and uncorrelated random networks. Using a well-defined Martingale approximation in diffusion-dominated regions of phase space, which is almost everywhere for the Voter model, this method is applied to
Pickering, William, Lim, Chjan
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Autoregressive models of singular spectral matrices
Automatica, 2012 This paper deals with autoregressive (AR) models of singular spectra, whose corresponding transfer function matrices can be expressed in a stable AR matrix fraction description [Formula: see text] with [Formula: see text] a tall constant matrix of full column rank and with the determinantal zeros of [Formula: see text] all stable, i.e. in [Formula: see
Anderson, Brian +3 more
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Remote Sensing, 2015 Ground-based estimates of aboveground wet (fresh) biomass (AWB) are an important input for crop growth models. In this study, we developed empirical equations of AWB for rice, maize, cotton, and alfalfa, by combining several in situ non-spectral and ...
Michael Marshall, Prasad Thenkabail
doaj +1 more source
Fast-Acquiring High-Quality Prony Series Parameters of Asphalt Concrete through Viscoelastic Continuous Spectral Models. [PDF]
Materials (Basel), 2022 Zhang Y, Sun Y.
europepmc +1 more source