Results 131 to 140 of about 7,700,165 (256)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Local Cross-validation for Spectrum Bandwidth Choice [PDF]
, 2000 We investigate an automatic method of determining a local bandwidth for non-parametric kernel spectral density estimates at a single frequency. This procedure is a modification of a cross-validation technique for global bandwidth choices, avoiding the ...
Velasco Gómez, Carlos, Velasco, Carlos
core +1 more source
The Study of Oil Film Thickness Measurement on Water Surface Based on Laser Raman Spectroscopy
, 2018 In order to realize the fast and non-contact detection of oil film thickness on water surface, a system based on laser Raman spectroscopy technologywas introduced in this paper. The 532 nm laser was used as the exciting source, and the result shows there
Feng Wei-wei +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Multi-agent Behaviour Segmentation via Spectral Clustering [PDF]
, 2007 18.02.14 KB. OK to add accepted version to spiral, AAAI permits.We examine the application of spectral clustering for breaking up the behaviour of a multi-agent system in space and time into smaller, independent elements.
Takács, B, Demiris, Y, Butler, S
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Latent Spectral Space Diffusion Models for Spatio-Temporal Predictive Learning
IEEE AccessSpatio-temporal forecasting is a critical challenge in various domains such as weather prediction, traffic flow analysis, and environmental monitoring, where understanding both spatial and temporal dependencies is key to accurate predictions.
Ming Zhang, Jie Wang, Qiao Liang
doaj +1 more source
Spectral calibration of exponential Lévy Models [1] [PDF]
We investigate the problem of calibrating an exponential Lévy model based on market prices of vanilla options. We show that this inverse problem is in general severely ill-posed and we derive exact minimax rates of convergence.
Denis Belomestny, Markus Reiß
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Abstract Signal Processing] (]]]])]]]–]]]
, 2005 In this paper, we develop and evaluate speech enhancement algorithms, which are based on supergaussian generalized autoregressive conditional heteroscedasticity (GARCH) models in the short-time Fourier transform (STFT) domain. We consider three different
Speech Spectral Modeling
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