Results 101 to 110 of about 324,518 (313)

Estimating spectral irradiance from measurements in seven spectral bands

, 2003
Accurate measurement and characterisation of fluctuations in the irradiance environment is important for many areas of optical remote sensing. This paper reports a method of estimating spectral irradiance over the VNIR region (400 - 1100nm) from the ...
Milton, E.J., Rollin, E.M.
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Spectral Transform for the Ising Model

Annales Henri Poincaré
We prove a correspondence between Ising models in a torus and the algebro-geometric data of a Harnack curve with a certain symmetry and a point in the real part of its Prym variety, extending the correspondence between dimer models and Harnack curves and their Jacobians due to Kenyon and Okounkov.
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Spectral calibration of exponential Lévy Models [1] [PDF]

We investigate the problem of calibrating an exponential Lévy model based on market prices of vanilla options. We show that this inverse problem is in general severely ill-posed and we derive exact minimax rates of convergence.
Denis Belomestny, Markus Reiß
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Enhancing beam structural damage detection using spectral moment values and spectral moment cumulative function models

Journal of Low Frequency Noise, Vibration and Active Control
Evaluation and identification of structural damage play a crucial role in ensuring the safety and reliability of structures. This study explores the application of spectral moment value analysis as a robust tool to assess and detect structural damage ...
Thanh Q Nguyen, Thuy T Nguyen, Phuoc T Nguyen   +2 more
doaj   +1 more source

Estimation of Spectral Solar Irradiance Toward Deriving Spectral Mismatch Factor Across Diverse Photovoltaic Technologies by Using Aerosol Optical Properties

Remote Sensing
This study presents a machine-learning framework for predicting spectral solar irradiance from 300 to 1100 nm using the random forest and neural network models.
Chang Ki Kim, Hyun-Goo Kim, Myeongchan Oh, Boyoung Kim, Chang-Yeol Yun   +4 more
doaj   +1 more source

Detecting Confounding in Multivariate Linear Models via Spectral Analysis

Journal of Causal Inference, 2018
We study a model where one target variable Y$Y$ is correlated with a vector X:=(X1,…,Xd)$\textbf{X}:=(X_1,\dots,X_d)$ of predictor variables being potential causes of Y$Y$.
Janzing Dominik, Schölkopf Bernhard
doaj   +1 more source