Results 41 to 50 of about 24,560 (299)
Graph Augmentation using Spectral moments
, 2023 Graph representational learning focuses on learning real value vectors that for nodes,edges or the graph, such that these vectors capture adequate information about these entities. Graph data augmentation, focuses on changing the structure or features in
Gopalakrishnan, Atul Anand
core
Acoustics of guttural fricatives in Arabic, Armenian, and Kurdish: A case in remote data collection
Laboratory PhonologyGutturals – uvulars, pharyngeals, and laryngeals – are relatively phonetically under-studied, with previous acoustic investigations being limited to a handful of languages (and mainly Arabic). The goal of this paper is twofold: (i) to provide an acoustic
Alexei Kochetov +3 more
doaj +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
BiophysicaTraditional drug design methods based on trial and error are costly and inefficient. The computational approach ToSS-MoDE (Topological Substructural Molecular Design) offers an alternative by linking molecular descriptors to biological activity.
Manuel Londa Vueba +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Spectral Features of Wolaytta Ejectives
LanguagesThis study analyzes the spectral properties of word-initial and intervocalic ejectives in Wolaytta, an Omotic language of southern Ethiopia. Using tokens embedded in three vowel contexts, we examined mean burst intensity, spectral moments, and vowel ...
Firew Elias, Derib Ado, Feda Negesse
doaj +1 more source
Inverse spectral problem for Jacobi operators and Miura transformation
Concrete Operators, 2021 We study a Miura-type transformation between Kac - van Moerbeke (Volterra) and Toda lattices in terms of the inverse spectral problem for Jacobi operators, which appear in the Lax representation for such systems.
Osipov Andrey
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source