Proximity Labelling Reveals the Compartmental Proteome of Murine Sensory Neurons
ABSTRACT Introduction Understanding the molecular architecture of peripheral sensory neurons is critical as we pursue novel drug targets against pain and neuropathy. Sensory neurons in the dorsal root ganglion (DRG) show extensive compartmentalization; thus, understanding each compartment—from the peripheral to central terminals—is key to this effort ...
Julia R. Sondermann +9 more
wiley +1 more source
Empirical Evaluation of UNet for Segmentation of Applicable Surfaces for Seismic Sensor Installation. [PDF]
Uzdiaev M +3 more
europepmc +1 more source
ABSTRACT This study quantifies the influence of alkali‐silica reaction (ASR) on the seismic fragility of prestressed concrete containment structures in nuclear power plants (NPPs). Global collapse was considered as the governing failure mode to maintain consistency with current risk assessment frameworks, and was captured using a finite element model ...
Chanyoung Kim +3 more
wiley +1 more source
Re-Purposing a Modular Origami Manipulator Into an Adaptive Physical Computer for Machine Learning and Robotic Perception. [PDF]
Wang J, Li S.
europepmc +1 more source
Abstract Approximately 1% of chronic lymphocytic leukemia (CLL) cases harbor a translocation juxtaposing the immunoglobulin heavy chain (IGH) and B‐cell lymphoma 3 (BCL3) loci. Aiming at comprehensive molecular characterization of IGH::BCL3‐positive B‐cell neoplasms, we here investigated samples from 84 patients using fluorescence in situ hybridization
Cosima Drewes +24 more
wiley +1 more source
Neural Oscillatory and Network Signatures of Age-Related Cognitive Decline Under Motor-Cognitive Dual-Task Conditions. [PDF]
Guo M +6 more
europepmc +1 more source
Plasma sEV‐GCC2 enables early detection and prognostic stratification of lung adenocarcinoma. This multicenter study integrates biomarker validation with functional evidence, supporting sEV‐GCC2 as a clinically relevant biomarker. ABSTRACT Emerging evidence suggests that GRIP and coiled‐coil domain‐containing two enriched small extracellular vesicles ...
Byeong Hyeon Choi +11 more
wiley +1 more source
A new paradigm for stratified cognitive assessment: fusing serum Raman spectroscopy and ensemble learning. [PDF]
Mo Y +10 more
europepmc +1 more source
Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang +8 more
wiley +1 more source
Odd-parity quasiparticle interference in the superconductive surface state of UTe<sub>2</sub>. [PDF]
Wang S +16 more
europepmc +1 more source

