Serum Metabolomics Study Reveals a Diagnostic Model for Lung Cancer Brain Metastasis
The overall workflow of noninvasive and efficient early diagnostic methods and key features of metabolic dysregulation associated with lung cancer brain metastasis, providing novel molecular insights into its pathogenesis and laying a foundation for future translational applications.
Hongxia Zhu, Yinuo Jin, Xin You, Qi Wang
wiley +1 more source
Critical Re-Examination of the Synthesis of Adamantyl Hydroperoxide. [PDF]
Nazarov I +5 more
europepmc +1 more source
ABSTRACT Background Conversion therapy, which seeks to achieve curative treatment following systemic therapy, is increasingly acknowledged in the management of unresectable hepatocellular carcinoma (HCC). However, validated criteria for predicting eligibility for conversion remain unclear. We investigated the utility of the recently proposed borderline
Yasuto Takeuchi +20 more
wiley +1 more source
Sequential Ag doping of Au25 - atomically precise nanoclusters induces alternating positive and negative shifts of the HOMO-LUMO gap. [PDF]
Fagan JW +5 more
europepmc +1 more source
A deep learning–clinical nomogram hybrid for predicting sentinel lymph node metastasis in melanoma
We developed MISSLE, a deep learning–clinical nomogram hybrid model, to predict sentinel lymph node metastasis in invasive cutaneous melanoma with a high area under the receiver operating characteristic curve of 0.950 on the test set. MISSLE identifies key histopathological features and integrates AI for improved clinical decision‐making.
Minh‐Khang Le +8 more
wiley +1 more source
Deciphering the biosynthetic pathways of lichen acids
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim +11 more
wiley +1 more source
The Convergence of Precision and Cognition in Biomedical AI. [PDF]
Pinto-Coelho L, Teixeira JP, Carmo JP.
europepmc +1 more source
Phase‐Field Fracture Simulation of Pressurized Concrete Microstructure
ABSTRACT Pressurized cracks in concrete have a significant impact on the safety and durability of concrete structures. The peak strength of concrete is reduced in the presence of pressurized cracks. However, conducting pressure‐coupled strength evaluation experiments requires extensive effort, and simulation tools can complement the time‐consuming and ...
Donghwi Eum +4 more
wiley +1 more source
Deep Learning-Driven Pathological Prediction of Lymph Node Metastasis in Patients with Head and Neck Squamous Cell Carcinoma Using Primary Whole Slide Images. [PDF]
Cao Z +8 more
europepmc +1 more source

