Results 111 to 120 of about 1,621,797 (256)

Spatio-Spectral Structure Tensor Total Variation for Hyperspectral Image Denoising and Destriping

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
This article proposes a novel regularization method, named spatio-spectral structure tensor total variation (${\text{S}_{3} \text{TTV}}$), for denoising and destriping hyperspectral (HS) images.
Shingo Takemoto, Kazuki Naganuma, Shunsuke Ono   +2 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Upper bounds for the spectral and norms of Cauchy-Toeplitz and Cauchy-Hankel matrices [PDF]

, 2004
- In this study we have given some upper bounds for the spectral and İ p norms of Cauchy-Toeplitz and Cauchy-Hankel matrices of the forms T[1/(1/2\mid i-j \mid)]_{nxn} and H[1/(1/2(ij))]_{nxn ...
Türkmen, Ramazan, Bozkurt, Durmuş, Solak, Süleyman   +2 more
core  

Spectral and pseudo-spectral methods for parabolic problems with non periodic boundary conditions

, 1981
The advection-diffusion equation is approximated by Chebyshev and Legendre spectral and pseudo-spectral methods. Stability results in the energy norm and error estimates in terms of the discretization parameter and of the regularity of the solution in ...
C. Canuto, QUARTERONI, ALFIO MARIA
core   +1 more source

Hyperspectral Image Denoising Based on Non-Convex Correlated Total Variation

Remote Sensing
Hyperspectral image (HSI) quality is generally degraded by diverse noise contamination during acquisition, which adversely impacts subsequent processing performance. Current techniques predominantly rely on nuclear norms and low-rank matrix approximation
Junjie Sun, Congwei Mao, Yan Yang, Shengkang Wang, Shuang Xu   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Beyond homogeneity: charting the landscape of heterogeneity in neurodevelopmental and psychiatric electroencephalography

Translational Psychiatry
Electroencephalography (EEG) has been thoroughly studied for decades in neurodevelopmental and psychiatric research. Yet its integration into clinical practice as a diagnostic/prognostic tool remains unachieved.
Aida Ebadi, Sahar Allouch, Ahmad Mheich, Judie Tabbal, Aya Kabbara, Gabriel Robert, Aline Lefebvre, Anton Iftimovici, Borja Rodríguez-Herreros, Nadia Chabane, Mahmoud Hassan   +10 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source