Results 61 to 70 of about 1,621,797 (256)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Disrupting gender norms in health systems: making the case for change [PDF]

open access: yes, 2019
Restrictive gender norms and gender inequalities are replicated and reinforced in health systems, contributing to gender inequalities in health. In this Series paper, we explore how to address all three through recognition and then with disruptive ...
Fielding-Miller, Rebecca   +34 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

On the bounds for the spectral norms of some special matrices [PDF]

open access: yes, 2004
http://sjam.selcuk.edu.tr/sjam/article/view/133In this paper, we have obtained lower and upper bounds for the spectral norms of Cauchy-Toeplitz and Cauchy-Henkel ...
Bozkurt, Durmuş   +2 more
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Singular Value Decomposition and Ligand Binding Analysis

open access: yesJournal of Spectroscopy, 2013
Singular values decomposition (SVD) is one of the most important computations in linear algebra because of its vast application for data analysis. It is particularly useful for resolving problems involving least-squares minimization, the determination of
André Luiz Galo   +1 more
doaj   +1 more source

Block Jacobi matrices and Titchmarsh-Weyl function [PDF]

open access: yesOpuscula Mathematica
We collect some results and notions concerning generalizations for block Jacobi matrices of several concepts, which have been important for spectral studies of the simpler and better known scalar Jacobi case.
Marcin Moszyński, Grzegorz Świderski
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

On limits of $L_p$-norms of an integral operator [PDF]

open access: yes, 1994
summary:A recurrence relation for the computation of the $L_p$-norms of an Hermitian Fredholm integral operator is derived and an expression giving approximately the number of eigenvalues which in absolute value are equal to the spectral radius is ...
Stavinoha, Pavel
core   +1 more source

An ultraspherical product integration-spectral collocation method for multidimensional partial Volterra integro-differential equations and its convergence analysis

open access: yesResults in Applied Mathematics
We present a reliable numerical method for solving multidimensional partial Volterra integro-differential equations (PVIDEs). This comprehensive approach integrates techniques from product integration, the Nyström method, and spectral collocation, all ...
Saman Bagherbana   +2 more
doaj   +1 more source

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