Results 61 to 70 of about 1,191,176 (295)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
This investigation attempts to estimate time-averaged shear wave velocity in the upper 30 m of surficial material, VS30, from the horizontal-to-vertical spectral ratios, HVSRs, of seismic observatory stations in the South Korean region. From 2016 to 2023,
Eric Yee, Chang-kyu Lee
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Rational weak mixing in infinite measure spaces
Rational weak mixing is a measure theoretic version of Krickeberg's strong ratio mixing property for infinite measure preserving transformations. It requires "{\tt density}" ratio convergence for every pair of measurable sets in a dense hereditary ring ...
Aaronson +5 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
基于汶川MS8.0地震后在窦圌山坡顶和坡脚测点获得的9次余震记录,通过基线校正、滤波处理,得到各余震记录的傅里叶谱谱比及质点运动轨迹图,结果表明山体的自振频率具有多阶段性,其最大位移方位会出现在山体的横向或走向上,且山体存在偏振效应。将9次余震东西向和南北的水平向加速度时程以10°为单位进行分解得到324条新的时程曲线,基于分解合成后的时程记录,将坡顶与坡脚相同分解角度下的时程作比值,对其峰值加速度比和傅里叶谱谱比进行分析,结果表明二者最大值所在的方位均与山体最大位移所在的方位相同 ...
Wei Wang +5 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Geometry of Noise in Color and Spectral Image Sensors
Digital images are always affected by noise and the reduction of its impact is an active field of research. Noise due to random photon fall onto the sensor is unavoidable but could be amplified by the camera image processing such as in the color ...
Axel Clouet +2 more
doaj +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The Renormalizable Three-Term Polynomial Inflation with Large Tensor-to-Scalar Ratio
We systematically study the renormalizable three-term polynomial inflation in the supersymmetric and non-supersymmetric models. The supersymmetric inflaton potentials can be realized in supergravity theory, and only have two independent parameters.
Li, Tianjun +3 more
core +1 more source

