Results 51 to 60 of about 42,140 (265)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Spectral triples and Toeplitz operators [PDF]

open access: yesProceedings of Frontiers of Fundamental Physics 14 — PoS(FFP14), 2016
We give examples of spectral triples, in the sense of A. Connes, constructed using the algebra of Toeplitz operators on smoothly bounded strictly pseudoconvex domains in \mathbb C^n , or the star product for the Berezin–Toeplitz quantization.
Englis, M., Falk, K., Iochum, Bruno
openaire   +6 more sources

Spectral Distances: Results for Moyal Plane and Noncommutative Torus

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2010
The spectral distance for noncommutative Moyal planes is considered in the framework of a non compact spectral triple recently proposed as a possible noncommutative analog of non compact Riemannian spin manifold.
Eric Cagnache, Jean-Christophe Wallet
doaj   +1 more source

κ-deformation, affine group and spectral triples [PDF]

open access: yesBanach Center Publications, 2012
A regular spectral triple is proposed for a two-dimensional $ $-deformation. It is based on the naturally associated affine group $G$, a smooth subalgebra of $C^*(G)$, and an operator $\caD$ defined by two derivations on this subalgebra. While $\caD$ has metric dimension two, the spectral dimension of the triple is one.
Iochum, Bruno, Masson, T., Sitarz, A.
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Spectral Correction of CPV Modules Equipped with GaInP/GaInAs/Ge Solar Cells and Fresnel Lenses

open access: yesApplied Sciences, 2017
Photovoltaic (PV) devices are spectrally selective, and their performance is influenced by unavoidable spectral variations. In addition, multijunction-based concentrating photovoltaic (CPV) devices show a strong spectral dependence due to the series ...
Marios Theristis   +3 more
doaj   +1 more source

Radiation shift from triple to quadruple frequency caused by the interaction of terahertz pulses with a nonlinear Kerr medium

open access: yesScientific Reports, 2022
High-intensity optical radiation propagation in a transparent dielectric medium causes the phenomena of pulse self-action and radiation generation at triple frequencies due to the cubic nonlinearity of the medium.
Ilya Artser   +5 more
doaj   +1 more source

Comprehensive, Continuous, and Vertical Measurements of Seawater Constituents with Triple-Field-of-View High-Spectral-Resolution Lidar

open access: yesResearch, 2023
Measuring the characteristics of seawater constituent is in great demand for studies of marine ecosystems and biogeochemistry. However, existing techniques based on remote sensing or in situ samplings present various tradeoffs with regard to the ...
Kai Zhang   +21 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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