Results 71 to 80 of about 42,140 (265)

The Bargmann type reduction for some Lax integrable two-dimensional generalization of the relativistic Toda lattice

Karpatsʹkì Matematičnì Publìkacìï, 2015
The possibility of applying the method of reducing upon finite-dimensional invariant subspaces, generated by the eigenvalues of the associated spectral problem, to some two-dimensional generalization of the relativistic Toda lattice with the triple ...
O.Ye. Hentosh
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Cross-Scale Transformer and Triple-View Attention Based Domain-Rectified Transfer Learning for EEG Classification in RSVP Tasks

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Rapid serial visual presentation (RSVP)-based brain-computer interface (BCI) is a promising target detection technique by using electroencephalogram (EEG) signals.
Jie Luo, Weigang Cui, Song Xu, Lina Wang, Huiling Chen, Yang Li   +5 more
doaj   +1 more source

Zeta Spectral Triples

We propose and investigate a strategy toward a proof of the Riemann Hypothesis based on a spectral realization of its non-trivial zeros. Our approach constructs self-adjoint operators obtained as rank-one perturbations of the spectral triple associated with the scaling operator on the interval $[λ^{-1}, λ]$.
Connes, Alain, Consani, Caterina, Moscovici, Henri   +2 more
openaire   +2 more sources

Spectral triples for the Sierpinski gasket

Journal of Functional Analysis, 2014
48 pages, 9 figures.
Cipriani, F, GUIDO, DANIELE, ISOLA, TOMMASO, Sauvageot, J.   +3 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Unoriented Spectral Triples

, 2017
Any oriented Riemannian manifold with a Spin-structure defines a spectral triple, so the spectral triple can be regarded as a noncommutative Spin-manifold. Otherwise for any unoriented Riemannian manifold there is the two-fold covering by oriented Riemannian manifold. Moreover there are noncommutative generalizations of finite-fold coverings.
openaire   +2 more sources

Spectral triples for nested fractals [PDF]

Journal of Noncommutative Geometry, 2017
It is shown that, for nested fractals [31], the main structural data, such as the Hausdorff dimension and measure, the geodesic distance (when it exists) induced by the immersion in \mathbb R^n , and the self-similar energy can all be recovered by ...
Guido, Daniele, Isola, Tommaso
openaire   +4 more sources