Results 81 to 90 of about 42,140 (265)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Equivariant Lorentzian Spectral Triples

open access: yes, 2006
We present examples of equivariant noncommutative Lorentzian spectral geometries. The equivariance with respect to a compact isometry group (or quantum group) allows to construct the algebraic data of a version of spectral triple geometry adapted to the situation of an indefinite metric. The spectrum of the equivariant Dirac operator is calculated.
Paschke, Mario, Sitarz, Andrzej
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

One-Dimensional Multi-Channel Photonic Crystal Resonators Based on Silicon-On-Insulator With High Quality Factor

open access: yesFrontiers in Physics, 2018
We have theoretically and experimentally demonstrated a Fabry-Pérot (FP) resonators based on a Si-air one-dimensional photonic crystal (1D PhC) with coupled triple-cavity modes (or defects).
Joaquin Faneca   +5 more
doaj   +1 more source

Sums of two-dimensional spectral triples

open access: yesMATHEMATICA SCANDINAVICA, 2007
We study countable sums of two-dimensional modules for the continuous complex functions on a compact metric space and show that it is possible to construct a spectral triple which gives the original metric back. This spectral triple will be finitely summable for any positive parameter.
Christensen, Erik, Ivan, Cristina
openaire   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

A new algebraic structure in the standard model of particle physics

open access: yesJournal of High Energy Physics, 2018
We introduce a new formulation of the real-spectral-triple formalism in non-commutative geometry (NCG): we explain its mathematical advantages and its success in capturing the structure of the standard model of particle physics. The idea, in brief, is to
Latham Boyle, Shane Farnsworth
doaj   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

Investigating Scattering Spectral Characteristics of GaAs Solar Cells by Nanosecond Pulse Laser Irradiation

open access: yesAerospace
Reliable power generation from solar cells is critical for spacecraft operation. High-energy laser irradiation poses a significant threat, as it can potentially cause irreversible damage to solar cells, which is difficult to detect remotely using ...
Hao Chang   +5 more
doaj   +1 more source

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