Results 51 to 60 of about 6,103 (201)

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source

A Spectral Unmixing Method by Maximum Margin Criterion and Derivative Weights to Address Spectral Variability in Hyperspectral Imagery

Remote Sensing, 2019
Limited to the low spatial resolution of the hyperspectral imaging sensor, mixed pixels are inevitable in hyperspectral images. Therefore, to obtain the endmembers and corresponding fractions in mixed pixels, hyperspectral unmixing becomes a hot spot in ...
Yang Shao, Jinhui Lan
doaj   +1 more source

System-level optimization in spectroscopic photoacoustic imaging of prostate cancer

Photoacoustics, 2022
This study presents a system-level optimization of spectroscopic photoacoustic (PA) imaging for prostate cancer (PCa) detection in three folds. First, we present a spectral unmixing model to segregate spectral system error (SSE). We constructed two noise
Yixuan Wu, Jeeun Kang, Wojciech G. Lesniak, Ala Lisok, Haichong K. Zhang, Russell H. Taylor, Martin G. Pomper, Emad M. Boctor   +7 more
doaj   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Graph-Based Adaptive Network With Spatial-Spectral Features for Hyperspectral Unmixing

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Hyperspectral unmixing aims to extract basic material (endmember) spectra and estimate their corresponding fractions (abundances) from observed pixels in hyperspectral images (HSIs).
Hua Dong, Xiaohua Zhang, Jinhua Zhang, Hongyun Meng, Licheng Jiao   +4 more
doaj   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

Advanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim, Seoyoon Song, Ali Zamat, Paul S. Pelkowski, Shivashankar Subramanian, Melissa Cadena, Sydney Fabrega, Meredith Brienen, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +10 more
wiley   +1 more source

Joint Local Block Grouping with Noise-Adjusted Principal Component Analysis for Hyperspectral Remote-Sensing Imagery Sparse Unmixing

Remote Sensing, 2019
Spatial regularized sparse unmixing has been proved as an effective spectral unmixing technique, combining spatial information and standard spectral signatures known in advance into the traditional spectral unmixing model in the form of sparse regression.
Ruyi Feng, Lizhe Wang, Yanfei Zhong
doaj   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

A Global-to-Local Spectral-Spatial Attention-Based Nonlinearity and Scaled Endmember Variability Parametric Learning Network for Unmixing

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Hyperspectral unmixing has attracted increasing attention in remote sensing applications. Unfortunately, significant unmixing residuals often arise from the coupled nonlinear mixing effects and spectral variability (SV), bringing challenges for reliably ...
Yi Zhao, Bin Yang
doaj   +1 more source