Results 11 to 20 of about 822,308 (195)

Single-Detector Spectrometer Using a Superconducting Nanowire. [PDF]

open access: yesNano letters (Print), 2020
Designing a spectrometer without the need for wavelength multiplexing optics can effectively reduce the complexity and physical footprint. On the basis of the computational spectroscopic strategy and combining a broadband-responsive dynamic detector, we ...
Ling-Dong Kong   +13 more
semanticscholar   +1 more source

Miniaturized spectrometer with intrinsic long-term image memory

open access: yesNature Communications
Miniaturized spectrometers have great potential for use in portable optoelectronics and wearable sensors. However, current strategies for miniaturization rely on von Neumann architectures, which separate the spectral sensing, storage, and processing ...
Gang Wu   +9 more
semanticscholar   +1 more source

Evolving mass spectra of the oxidized component of organic aerosol: results from aerosol mass spectrometer analyses of aged diesel emissions

open access: yes, 2008
The species and chemistry responsible for secondary organic aerosol (SOA) formation remain highly uncertain. Laboratory studies of the oxidation of individual, high-flux SOA precursors do not lead to particles with mass spectra (MS) matching those of ...
A. Sage   +3 more
semanticscholar   +1 more source

Quantum diamond spectrometer for nanoscale NMR and ESR spectroscopy [PDF]

open access: yesNature Protocols, 2019
Nitrogen-vacancy (NV) quantum defects in diamond are sensitive detectors of magnetic fields. Owing to their atomic size and optical readout capability, they have been used for magnetic resonance spectroscopy of nanoscale samples on diamond surfaces. Here,
D. Bucher   +6 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Ultrahigh-resolution on-chip spectrometer with silicon photonic resonators

open access: yesOpto-Electronic Advances, 2020
A compact spectrometer on silicon is proposed and demonstrated with an ultrahigh resolution. It consists of a thermally-tunable ultra-high-Q resonator aiming at ultrahigh resolution and an array of wideband resonators for achieving a broadened working ...
Long Zhang   +5 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Vernier spectrometer using counterpropagating soliton microcombs [PDF]

open access: yesScience, 2018
Making a (precision) measure of light When measuring length, we learn in school that a vernier scale that uses two rulers, slightly offset, can reduce human estimation error and improve the resolution of a measurement. Yang et al.
Qifan Yang   +10 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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