Results 81 to 90 of about 1,810,207 (355)

Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]

, 2018
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L, Chalkley, Robert J, Forester, Craig M, Oses-Prieto, Juan A, Phillips, Nancy J, Ruggero, Davide, Urisman, Anatoly, Zhang, Li, Zhao, Qian   +8 more
core   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Determination of trace fluoroquinolones in water solutions and in medicinal preparations by conventional and synchronous fluorescence spectrometry

Open Chemistry, 2018
Simple, rapid and sensitive and synchronous fluorescence spectrometry (SFS) were developed for determination the fluoroquinolones of ciprofloxacin (CIP), norfloxacin (NOR) and enrofloxacin (ENR) separately in water solutions and in medicinal preparations.
Yao Ting, Wang Hongling, Si Xuejing, Yin Shengnan, Wu Tunhua, Wang Ping   +5 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Optimization of an in vitro Pseudomonas aeruginosa Biofilm Model to Examine Antibiotic Pharmacodynamics at the Air-Liquid Interface

npj Biofilms and Microbiomes
Pseudomonas aeruginosa is an important cause of lower respiratory tract infections, such as ventilator-associated bacterial pneumonia (VABP). Using inhaled antibiotics to treat VABP can achieve high drug concentrations at the infection site while ...
Xing Tan, Yanqin Huang, Amisha Rana, Nidhi Singh, Taylor C. Abbey, Hui Chen, Peter T. Toth, Zackery P. Bulman   +7 more
doaj   +1 more source

Study of Araucaria angustifolia nuts by Gamma Spectrometry and X-Ray Fluorescence

Revista de la Sociedad Científica del Paraguay, 2019
The seed of Araucaria angustifolia is largely produced and consumed in Parana state, Brazil. It has an estimated annual consumption of approximately 0.167 kg per capita. The samples of seeds were acquired in 8 different commercial points of Londrina city
Edher Zacarías Herrera, Avacir Casanova Andrello, Carlos Roberto Appoloni   +2 more
doaj   +1 more source

Pressurised Liquid Extraction of Capsaicinoids from Peppers [PDF]

, 2006
Se presenta el desarrollo de un método de extracción de capsaicinoides en pimientos mediante la técnica de extracción mediante fluidos ...
Fernández Barbero, Gerardo, García Barroso, Carmelo, Palma Lovillo, Miguel   +2 more
core   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Wavelength-scale stationary-wave integrated Fourier-transform spectrometry [PDF]

, 2007
Spectrometry is a general physical-analysis approach for investigating light-matter interactions. However, the complex designs of existing spectrometers render them resistant to simplification and miniaturization, both of which are vital for applications
A Bruyant, A Labeyrie, Alain Morand, AM Kadin, D Gabor, D Knipp, Etienne le Coarer, G Lippmann, G Lippmann, G Sagnac, Gilles Lérondel, Grégory Leblond, GW Stroke, HE Ives, I Stefanon, Ilan Stefanon, J Bland-Hawthorn, Jean Marc Fedeli, M Froggatt, ML Junttila, P Connes, Pascal Royer, Pierre Benech, Pierre Kern, RF Wolffenbuttel, RG Lyons, S Rommeluere, Sylvain Blaize, YN Denisyuk   +28 more
core   +4 more sources

Direct Detection of Fungal Siderophores on Bats with White-Nose Syndrome via Fluorescence Microscopy-Guided Ambient Ionization Mass Spectrometry

PLoS ONE, 2015
White-nose syndrome (WNS) caused by the pathogenic fungus Pseudogymnoascus destructans is decimating the populations of several hibernating North American bat species.
Samantha J. Mascuch, W. J. Moree, Cheng-Chih Cheng-Chih Hsu, Cheng-Chih Cheng-Chih Hsu, Gregory G. Turner, Tina L. Cheng, David S. Blehert, A. M. Kilpatrick, Winifred F. Frick, Michael J. Meehan, Michael J. Meehan, Pieter C Dorrestein, Pieter C Dorrestein, L. Gerwick   +13 more
semanticscholar   +1 more source