Results 31 to 40 of about 816,424 (266)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

COMPUTER SIMULATION OF GAMMA-RAY DETECTOR BASED ON SCINTILLATION CRYSTALS AND SILICON PHOTOMULTIPLIERS [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2018
Subject of Research. The paper considers the principles of realization of the gamma-radiation detector based on a silicon photoelectron multiplier and a scintillation crystal with the use of an optical matching scheme. Method.
Bokatyi I.O.   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Spectroscopic Study and Analysis of the Content of Residue Elements in Marinol RG 1240 Oil after Working in Various Types of Engines

open access: yesScientific Journal of Gdynia Maritime University, 2017
During exploitation, the engine oil undergoes the irreversible aging process that is – degradation. The speed of this process is affected by many factors such as high temperature, pressure, power output, oxygen from the air, mechanical shear forces, type,
M. Malinowska
doaj  

Spectroscopic and Spectrometric Applications for the Identification of Bioactive Compounds from Vegetal Extracts

open access: yesApplied Sciences, 2021
The use of spectroscopic and spectrometric techniques to isolate, quantify, and characterize bioactive compounds from edible plants has become a common and mandatory activity in food chemistry.
José Daniel Lozada-Ramírez   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Spectral Library of Maize Leaves under Nitrogen Deficiency Stress

open access: yesData, 2022
Maize crops occupy an important place in world food security. However, different conditions, such as abiotic stress factors, can affect the productivity of these crops, requiring technologies that facilitate their monitoring.
Maria C. Torres-Madronero   +10 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Colours of Octopus: Using Spectral Data to Measure Octopus Camouflage

open access: yesVision, 2022
No animal can so effectively camouflage in such a wide range of environments as the octopus. Thanks to their highly malleable skin, they are capable of adapting their body patterns to the brightness and texture of their immediate environment, and they ...
Luis Nahmad-Rohen   +2 more
doaj   +1 more source

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