Results 81 to 90 of about 48,569 (262)
For the simultaneous determination of a binary mixture of amlodipine (AM) and atenolol (AT) in tablets, two approaches were accessible. The first method is the second derivative of the ratio spectra (2DD) that obtained via dividing the absorption ...
Shilan Omer +2 more
doaj
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Coupling biosynthetic noncanonical amino acid production with genetic code expansion enables site‐specific incorporation of azatryptophans into PET‐degrading enzymes (PETases). By isosteric single‐atom editing of a conserved tryptophan, AzaPETases break the activity–stability trade‐off, delivering higher catalytic efficiency at elevated temperature and
Elwy H. Abdelkader +3 more
wiley +2 more sources
Methyl salicylate and sorbitol were taken as coating agents. Caenorhabditis elegans was taken as an animal model. The coated agents were applied in C. elegans. The life span study in C. elegans proves the authenticity of MS and SL. MS and SL extended the post‐harvest life of cucumber for 14 days.
Chirayu H. Trivedi +3 more
wiley +1 more source
Rapid Spectrophotometric Determination of Phenoxazine
A rapid high sensitive and inexpensive economic method has been developed for the Determination of phenoxazine by using molecular spectrophotometry. The method is based on the oxidation of phenoxazine by potassium (meta)periodate in acidic medium.
Baghdad Science Journal
doaj +1 more source
Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
An accurate and sensitive spectrophotometric method has been developed for the determination of cefotaxime (CEF) in pure and pharmaceutical samples.
Sumayha Mohammed Abbas +1 more
doaj
A simple, accurate and low cost spectrophotometric method is proposed for the determination of the synthesized paracetamol derivative; 4-acetamidophenyl N’-(sulphanilamide) acetate (APSA) in biological fluids. The spectrophotometric method is based on a
Bhavna Ajay Shah +2 more
doaj
Spectrophotometric determination of favipiravir in presence of its acid hydrolysis product. [PDF]
Sharaf YA +3 more
europepmc +1 more source

