Results 41 to 50 of about 47,074 (301)

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

open access: yesAdvanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu   +6 more
wiley   +1 more source

Analytical method development of pitavastatin-loaded SNEDDS formulation: Multivariate analysis regarding ultraviolet spectrophotometry analysis

open access: yesJournal of Food and Pharmaceutical Sciences, 2019
Herein, this work aimed to develop and assess feasibility of multivariate model of partial least square analysis for specific quantification of pitavastatin (PVT)-loaded self-nano emulsion (SNE) formulation using UV Vis spectrophotometry. PVT loaded into
Kuncahyo I   +4 more
doaj   +1 more source

A FEROS spectroscopic study of the extreme O supergiant He 3-759

open access: yes, 2009
We present a study of the extreme O-type supergiant He 3-759 using new high-resolution FEROS data, revealing that it is a near spectroscopic twin of HD 151804 (O8 Iaf).
Arnaboldi   +34 more
core   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng   +12 more
wiley   +1 more source

Time-Resolved Ultraviolet Observations of the Globular Cluster X-ray Source in NGC 6624: The Shortest Known Period Binary System

open access: yes, 1997
Using the Faint Object Spectrograph (FOS) aboard the Hubble Space Telescope, we have obtained the first time-resolved spectra of the King et al. ultraviolet-bright counterpart to the 11-minute binary X-ray source in the core of the globular cluster NGC ...
Auriere M.   +8 more
core   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Ion‑Mediated Structural Engineering of Hydrogel Interfaces for Tunable Mechanical and Analyte Diffusion Properties in Electrochemical Biosensors

open access: yesAdvanced Materials, EarlyView.
An ion‐mediated structural engineering strategy enables versatile modulation of PVA–Alginate hydrogel microstructure. We systematically examine how different ion combinations affect hydrogel mechanical properties and analyte diffusivity. Applying this novel strategy to hydrogel as the outer membrane in an electrochemical glucose biosensor allows ...
Dongwook Lee   +14 more
wiley   +1 more source

Development and validation of RP-LC and uv spectrophotometric methods to assay bromopride in oral and injectable solutions

open access: yesQuímica Nova, 2010
A reversed-phase liquid chromatographic (LC) and ultraviolet (UV) spectrophotometric methods were developed and validated for the assay of bromopride in oral and injectable solutions. The methods were validated according to ICH guideline.
Márcia Camponogara Fontana   +6 more
doaj   +1 more source

A Fluorescent and Colorimetric Chemosensor for Hg2+ Based on Rhodamine 6G With a Two-Step Reaction Mechanism

open access: yesFrontiers in Chemistry, 2020
A fluorescent and colorimetric chemosensor L based on rhodamine 6G was designed, synthesized, and characterized. Based on a two-step reaction, the chemosensor L effectively recognized Hg2+.
Cui-Bing Bai   +15 more
doaj   +1 more source

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu   +8 more
wiley   +1 more source

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