Results 171 to 180 of about 325,267 (403)

Reduced Wolf-Rayet Line Luminosities at Low Metallicity

open access: yes, 2005
New NTT/EMMI spectrophotometry of single WN2-5 stars in the Magellanic Clouds are presented, from which HeII 4686 line luminosities have been derived, and compared with observations of other Magellanic Cloud WR stars.
Barba   +73 more
core   +1 more source

Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
Selenium electrophilic center intelligently responds to different ratio of biological electron donors/receptors in cancer cells and normal cells to achieve highly effective and less toxic chemotherapy. Abstract Designing drugs to intelligently respond to different ratio of biological electron donors/receptors in cancer cells and normal cells is a ...
Xiaoyu Qin   +8 more
wiley   +1 more source

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

open access: yesAdvanced Science, EarlyView.
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren   +15 more
wiley   +1 more source

Structural Basis and Mechanism of a Unique Haemophore in the Haem‐Iron Acquisition by Riemerella anatipestifer

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This study reveals the structural basis and mechanism of RhuH as a haemophore in Riemerella anatipestifer. Secreted by outer membrane vesicles (OMVs), RhuH captures haem with high affinity from host hemoglobin in two forms: a) released from OMVs, binding and transferring haem to outer membrane receptor, and b) haem‐bound on the OMVs surface, returning ...
Mengying Wang   +19 more
wiley   +1 more source

Investigation of sulfated glycosaminoglycans and their agarose gel electrophoresis patterns from plants extracts

open access: yesJournal of Associated Medical Sciences, 2018
Background: Many kinds of sulfated glycosaminoglycans (GAGs) play an essential role in both physiological and pathological conditions. Most of them are obtained from animal sources, and used as nutraceuticals or therapeutic applications.
Kanyamas Choocheep   +5 more
doaj  

Lactylation‐Driven HECTD2 Limits the Response of Hepatocellular Carcinoma to Lenvatinib

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
HECTD2 serves as an E3 ubiquitin ligase of KEAP1 to facilitate the antioxidative response and contributes to lenvatinib resistance in hepatocellular carcinoma. Lactylation of histone 3 on lysine residue 18 drives HECTD2 transcription. Targeting HECTD2 using PLGA‐PEG‐based nanoparticles offers novel strategies to overcome lenvatinib resistance in ...
Runyu Dong   +12 more
wiley   +1 more source

Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two‐Photon Fluorescent Probe

open access: yesAdvanced Science, EarlyView.
A single dual‐emission two‐photon fluorescent probe is designed for simultaneously tracking tyrosinase (TYR) and adenosine triphosphate (ATP). With the help of this probe, the intricate correlation and regulatory mechanism between TYR and ATP during oxidative stress is uncovered.
Hong Huang   +12 more
wiley   +1 more source

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