Results 271 to 280 of about 217,951 (354)

4‐O‐Methylglucuronoxylan from Hygrophila Ringens var. Ringens Seeds: Chemical Composition and Anti‐Inflammatory Activity

open access: yesMacromolecular Bioscience, EarlyView.
4‐O‐Methylglucuronoxylan from Hygrophila ringens var. ringens is found to inhibit the serum albumin denaturation, inflammatory cytokines, and release of reactive oxygen species by activation of mitogen‐activated protein kinases without having significant macrophage cytotoxicity.
Vo Hoai Bac   +8 more
wiley   +1 more source

Investigating How All‐Trans Retinoic Acid Polycaprolactone (atRA‐PCL) Microparticles Alter the Material Properties of 3D Printed Fibrin Constructs

open access: yesMacromolecular Bioscience, EarlyView.
The presence of all‐trans retinoic acid (atRA) in polycaprolactone (PCL) microparticles can promote the degradation of fibrin constructs. This highlights the need for a more careful consideration of the effects that drug‐releasing microparticles can have on the scaffold materials when designing smart bioinks for the 3D printing of tissue constructs ...
Maria V. Hangad   +4 more
wiley   +1 more source

Synthesis of Poly (2‐hydroxyethyl ethyleneimine) and Its Mucoadhesive Film Formulations When Blended with Chitosan for Buccal Delivery of Haloperidol

open access: yesMacromolecular Bioscience, EarlyView.
Mucoadhesive chitosan‐poly(2‐hydroxyethyl ethyleneimine) (P2HEEI) films were developed for buccal delivery of haloperidol. P2HEEI is synthesized by reacting linear polyethyleneimine with 2‐bromoethanol, achieving high solubility, low glass transition temperature, and biocompatibility.
Sitthiphong Soradech   +2 more
wiley   +1 more source

Temperature Sensitive Pluronic F127‐Based Gels Incorporating Natural Therapeutic Agents

open access: yesMacromolecular Materials and Engineering, EarlyView.
Pluronic F127‐based injectable gels are designed for therapeutic applications. The curcumin encapsulation efficiency and stability of formulations are investigated in aqueous environment and in acetic acid solutions. The viscoelasticity of gels, correlated with the network structure, is influenced by xanthan gum or acetic acid addition.
Alexandra Lupu   +5 more
wiley   +1 more source

Design and Characterization of Decellularized Caprine Liver Matrix Constructs for Liver Tissue Engineering

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study develops decellularized caprine liver scaffolds, preserving ECM components like collagen and GAGs. The scaffolds are combined with Chitosan‐PVA hydrogels, optimized via FT crosslinking, thus exhibiting shear‐thinning behavior, enhanced mechanical properties, and biocompatibility, supporting HepG2 cell adhesion, proliferation, and hepatic ...
Supriya Bhatt   +3 more
wiley   +1 more source

Poly(amino acid) Synthesis from 2,5‐Diketopiperazines for Acid‐Actuated Drug Release

open access: yesMacromolecular Materials and Engineering, EarlyView.
The ring‐opening polymerization (ROP) of 2,5‐diketopiperazines (2,5‐DKPs) to yield poly(amino acids) is reported. This route to poly(amino acids) has circularity, and permits the straightforward production of nanoparticles for controlled release applications.
Patrick A. Wall   +3 more
wiley   +1 more source

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