Results 31 to 40 of about 154,283,390 (201)

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Preparation and evaluation of bovine serum albumin-protected copper sulfide nanoparticles

Biomedical Analysis
This study aimed to prepare bovine serum albumin (BSA)-protected copper sulfide nanoparticles (CuS@BSA), systematically characterize their physicochemical properties, and preliminarily evaluate their in vitro antitumor activity, providing an experimental
Shengli Shen, Lei Wu, Jun Zhang, Haoran Ye, Ying Chen   +4 more
doaj   +1 more source

L-cysteine modified silver nanoparticles for selective and sensitive colorimetric detection of vitamin B1 in food and water samples

Heliyon, 2020
The use of L-cysteine modified silver nanoparticles (Cys-capped AgNPs) as a colorimetric probe for determination of vitamin B1 (thiamine) is described in the present work.
Beeta Rani Khalkho, Ramsingh Kurrey, Manas Kanti Deb, Kamlesh Shrivas, Santosh Singh Thakur, Shamsh Pervez, Vikas Kumar Jain   +6 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Spectrophotometry for cerebrospinal fluid pigment analysis [PDF]

, 2006
The use of spectrophotometry for the analysis of the cerebrospinal fluid (CSF) is reviewed. The clinically relevant CSF pigments--oxyhemoglobin and bilirubin--are introduced and discussed with regard to clinical differential diagnosis and potentially ...
Sharpe, L.T., Petzold, A., Keir, G.
core  

FTIR Spectrophotometry as a Green Tool for Quantitative Analysis of Drugs: Practical Application to Amoxicillin

Journal of Chemistry, 2018
Amoxicillin is an antimicrobial agent that belongs to the penicillin compounds. Its bactericidal action causes a destruction of the cell wall of bacteria.
Stefany Fanelli, Alexander Zimmermann, Eliane Gandolpho Totóli, Hérida Regina Nunes Salgado   +3 more
doaj   +1 more source

Kidney‐Targeted Cilastatin Nanoparticles Inhibit DPEP1‐Mediated Ferroptosis for Acute Kidney Injury Therapy

Advanced Science, EarlyView.
In this study, MPDA NPs were engineered to encapsulate CTT. To further increase renal accumulation of CTT, L‐serine was conjugated to the surface of the MPDA nanoparticles (CTT/MPDA@L‐Ser NPs). CTT/MPDA@L‐Ser NPs inhibit DPEP1 activity, thereby restoring ferroptosis defense mechanisms through upregulation of GPX4 and SLC7A11 expression, ultimately ...
Wanbing Qin, Jiaqi Huang, Manting Zhang, Wanchun Yang, Mingwei Xu, Chi Jiang, Jiekai Li, Jinjuan Wen, Qibin Huang, Shiqi Wen, Weidong Wang, Junbing He, Qinghua Liu   +12 more
wiley   +1 more source

Quantitative analysis of neodymium, uranium, and palladium in nitric acid solution by reflection absorption spectrophotometry [PDF]

, 2013
Quantitative analysis of Nd, U, or Pd in 3 mol dm[−3] (M) HNO3 was performed by reflection absorption spectrophotometry at ultraviolet–visible–near-infrared (UV/Vis/NIR) region.
Fujii, Toshiyuki, Morita, Yasuji, Yamana, Hajimu, Uehara, Akihiro, Egusa, Souichirou   +4 more
core   +1 more source

Quantitative analysis of pharmaceutical products by spectrophotometry in the infrared region: a practical review [PDF]

Quality control in the chemical-pharmaceutical industry to identify and quantify the active ingredient has fundamental importance to guarantee the quality of the final product.
Kogawa, Ana, Salgado, Hérida Regina Nunes   +1 more
core   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source