Results 41 to 50 of about 19,025 (294)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Logarithm of a Non-Singular Complex Matrix via the Dunford–Taylor Integral

open access: yesAxioms, 2022
Using the Dunford–Taylor integral and a representation formula for the resolvent of a non-singular complex matrix, we find the logarithm of a non-singular complex matrix applying the Cauchy’s residue theorem if the matrix eigenvalues are known or a ...
Diego Caratelli, Paolo Emilio Ricci
doaj   +1 more source

Spectral Gaps for Periodic Elliptic Operators with High Contrast: an Overview [PDF]

open access: yes, 2002
We discuss the band-gap structure and the integrated density of states for periodic elliptic operators in the Hilbert space $L_2(\R^m)$, for $m \ge 2$.
Hempel, Rainer, Post, Olaf
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

An inverse problem for a second-order differential equation in a Banach space

open access: yesAbstract and Applied Analysis, 2004
We consider the problem of determining the unknown term in the right-hand side of a second-order differential equation with unbounded operator generating a cosine operator function from the overspecified boundary data.
Y. Eidelman
doaj   +1 more source

On indices of the Dirac operator in a non-Fredholm case

open access: yes, 1996
The Dirac Hamiltonian with the Aharonov-Bohm potential provides an example of a non-Fredholm operator for which all spectral asymmetry comes entirely from the continuous spectrum.
Moroz, Alexander
core   +1 more source

Finite-dimensional perturbations of linear operators and some applications to boundary integral equations [PDF]

open access: yes, 1999
Finite-dimensional perturbing operators are constructed using some incomplete information about eigen-solutions of an original and/or adjoint generalized Fredholm operator equation (with zero index).
Mikhailov, SE
core   +1 more source

Time-resolved optical spectrum for transient resonant light scattering [PDF]

open access: yesPhysical Review E, 1994
A general formula of the time-resolved optical spectrum for transient resonant light scattering is derived systematically by means of the operator algebra within the formalism of nonequilibrium thermo field dynamics (NETFD). The formula is applied to an analytically solvable model of the localized electron and phonon system, i.e., second-order light ...
, Arimitsu, , Arimitsu
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

A note on the spectral operators of scalar type and semigroups of bounded linear operators

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
It is shown that, for the spectral operators of scalar type, the well-known characterizations of the generation of C0- and analytic semigroups of bounded linear operators can be reformulated exclusively in terms of the spectrum of such operators, the ...
Marat V. Markin
doaj   +1 more source

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