Results 181 to 190 of about 7,764,522 (352)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

mJ-level 7-octave ultraflat white laser encompassing 200-25,000 nm. [PDF]

Light Sci Appl
Hong L, Feng R, Liu Y, Liu J, Qian J, Peng Y, Leng Y, Li R, Li ZY.   +8 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

A Buffered LC-MS Method for Resolving and Quantifying Albiflorin and Paeoniflorin. [PDF]

Biomed Chromatogr
Gazizova A, Altincubuk EH, Oppermann C.
europepmc   +1 more source

Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative.

Archives of General Psychiatry, 2011
K. Merikangas, R. Jin, Jian-ping He, R. C. Kessler, Sing Lee, N. Sampson, M. Viana, L. Andrade, Chi‐yi Hu, E. Karam, M. Ladea, M. Medina-Mora, Y. Ono, J. Posada-Villa, R. Sagar, J. E. Wells, Z. Zarkov   +16 more
semanticscholar   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source

MapsTorch: automatic differentiation for X-ray fluorescence data analysis. [PDF]

J Synchrotron Radiat
Yin X, Di Z, Antipova O, Chen S, Jiang Y, Glowacki A.   +5 more
europepmc   +1 more source

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

Science Translational Medicine, 2017
T. Sheahan, A. Sims, Rachel L. Graham, Vineet D. Menachery, Lisa E. Gralinski, J. Case, S. Leist, K. Pyrć, Joy Y. Feng, Iva Trantcheva, R. Bannister, Yeojin Park, D. Babusis, M. Clarke, R. Mackman, Jamie E. Spahn, Christopher A. Palmiotti, D. Siegel, A. Ray, T. Cihlář, R. Jordan, M. Denison, R. Baric   +22 more
semanticscholar   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Tunable Wavelength-Multiplexed Dual-Frequency Bound Pulse in a Carbon-Nanotube-Based Fiber Laser. [PDF]

Micromachines (Basel)
Wang L, Hu G, Wang Y, Chen G, Xuan L, Zhou Z, Yu J.   +6 more
europepmc   +1 more source