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The mutational constraint spectrum quantified from variation in 141,456 humans
Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that are crucial for the function of an organism will be depleted of such variants in natural ...
Konrad J Karczewski +2 more
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Autism Spectrum Disorder: A Review.
Journal of the American Medical Association (JAMA), 2023Importance Autism spectrum disorder (ASD), characterized by deficits in social communication and the presence of restricted, repetitive behaviors or interests, is a neurodevelopmental disorder affecting approximately 2.3% children aged 8 years in the US ...
T. Hirota, B. King
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The global spectrum of plant form and function
Sandra Myrna Díaz +2 more
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The contribution of de novo coding mutations to autism spectrum disorder
Ivan Iossifov +2 more
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The spectrum of inflammatory responses
Science, 2021Description Inflammation is an integral part of animal biology. It provides critical protection from adverse environmental factors by enforcing the defense of homeostasis and the functional and structural integrity of tissues and organs.
R. Medzhitov
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Spectrum and Pseudo-Spectrum [PDF]
In this book all Hilbert spaces will be assumed to separable for simplicity. In this section we review some basic definitions and properties; we refer to Kato (Perturbation theory for linear operators, Die Grundlehren der mathematischen Wissenschaften, Band 132. Springer, New York, 1966), Reed and Simon (Methods of modern mathematical physics.
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An absorption profile centred at 78 megahertz in the sky-averaged spectrum
Nature, 2018After stars formed in the early Universe, their ultraviolet light is expected, eventually, to have penetrated the primordial hydrogen gas and altered the excitation state of its 21-centimetre hyperfine line.
J. Bowman +4 more
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Let T be a linear operator whose domain D(T) and range R(T) both lie in the same complex linear topological space X. We consider the linear operator $${T_\lambda } = \lambda I - T,$$ , where λ is a complex number and I the identity operator. The distribution of the values of λ for which T λ has an inverse and the properties of the inverse when ...
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