Results 31 to 40 of about 6,104,001 (288)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Sex and Sexuality in the United States: A Brief History of Culture Wars [PDF]

, 2011
The HIV/AIDS pandemic has entered its thirtieth year; sex trafficking persists as an $8 billion industry (May 2006); unwanted pregnancies and transmission of sexually transmitted infections (STIs) continuously occur due to a lack of simple knowledge ...
Marcus, Olivia
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Pancreatic Cancer: A Review of Current Treatment and Novel Therapies

Journal of Investigative Surgery, 2023
Pancreatic cancer is one of the leading causes for cancer-related deaths in the United States. Majority of patients present with unresectable or metastatic disease.
Hordur Mar Kolbeinsson, Sreenivasa Chandana, G. Paul Wright, Mathew Chung   +3 more
doaj   +1 more source

Archaeology from Space: Advanced Satellite Imagery Through the Work of Sarah Parcak [PDF]

, 2017
The ancient past and the technological future come together in “space archaeology.” Focusing on the colorful career of Sarah Parcak, this article shows how advanced satellite imagery is being used to discover new archaeological sites—as well as to ...
Philibert, Rebecca
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Palpable Abdominal Mass is a Renal Oncocytoma: Not All Large Renal Masses are Malignant

Case Reports in Urology, 2019
A 59-year-old woman presented with abdominal pain and a palpable abdominal mass. Initial imaging revealed a 14cm solid, enhancing renal mass and suspicion for liver and bone metastases.
Sumi Dey, Sabrina L. Noyes, Ghayas Uddin, Brian R. Lane   +3 more
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Open-path Dual-Comb Spectroscopy Observations of Greenhouse Gas Spatial and Temporal Variability over Km-scale Paths [PDF]

EPJ Web of Conferences
A dual-comb spectrometer is deployed for kilometer scale open-path measurements of CO2 and CH4 at building-top heights in Manhattan, New York City. The system operated for more than 3 months in summer 2023 and more than 1 month in winter 2024.
Kasic James, Malarich Nathan, Mead Griffin, Baumann Esther, Syed Saad, Washburn Brian, Cossel Kevin, Coddington Ian   +7 more
doaj   +1 more source