Results 81 to 90 of about 6,298,979 (361)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Integrating Gender Identity and Sexual Orientation in Population-Based Administrative Data

open access: yesInternational Journal of Population Data Science
Information regarding biological sex is collected for administrative and clinical purposes, and often is conflated with gender in clinical encounters as well as in population-based data studies. Sex is collected as either ‘male’ or ‘female’, adhering to
Mikayla Hunter   +2 more
doaj   +1 more source

The Bohl spectrum for nonautonomous differential equations [PDF]

open access: yes, 2016
We develop the Bohl spectrum for nonautonomous linear differential equation on a half line, which is a spectral concept that lies between the Lyapunov and the Sacker--Sell spectrum.
Doan, Thai Son   +2 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Evaluation of Trigger Tool Methodology Related to Adverse Drug Events in Hospitalized Patients

open access: yesPatient Safety, 2019
Purpose: To determine why an inpatient has had one of the following occurrences in the electronic health record due to an adverse drug event (ADE): international normalized ratio (INR) > 6, plasma blood glucose ≤ 50 mg/dL, or naloxone administration use.
Sara Kolc Brown   +3 more
doaj   +1 more source

The Use and Abuse of Archaeology to Promote Nazi Nationalist Goals [PDF]

open access: yes, 2011
By appealing to the people, and restoring a sense of pride through nationalism, Hitler and his Nazi party gained immense popularity. In this article, I explore one of the Nazi party\u27s most influential, yet not well known or studied in depth, methods ...
Bouchard, Matt
core   +1 more source

Harrison-Z'eldovich primordial spectrum is consistent with observations [PDF]

open access: yes, 2010
Inflation predicts primordial scalar perturbations with a nearly scale-invariant spectrum and a spectral index approximately unity (the Harrison--Zel'dovich (HZ) spectrum).
A. A. Starobinsky   +8 more
core   +4 more sources

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

2012: The End of the World as We Know It? [PDF]

open access: yes, 2013
Many so-called “2012 doomsayers theorists,” such as John Major Jenkins and Jose Arguelles successfully convinced a portion of the modern Western world that the ancient Maya had predicted the end of the world.
French, Evelyn
core   +1 more source

Luminosity Spectrum Reconstruction at Linear Colliders [PDF]

open access: yes, 2013
A good knowledge of the luminosity spectrum is mandatory for many measurements at future e+e- colliders. As the beam-parameters determining the luminosity spectrum cannot be measured precisely, the luminosity spectrum has to be measured through a gauge ...
Poss, Stéphane, Sailer, André
core   +2 more sources

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