Results 81 to 90 of about 6,104,001 (288)
HIV Knowledge among Muslim University Women [PDF]
, 2015 While studies have shown that HIV infections are increasing in Muslim countries, especially among the young population (Abu-Moghli et al. 2010), the prevalence of HIV infection among young Muslims in the United States is poorly understood.
Singh, Subha
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
How Patients Think: Assessing Clinician Competence in University Settings [PDF]
, 2015 The past academic year of 2014–2015 I completed an independent research study to observe how patients assess clinician competence within a university setting. The goal of the research was twofold: first, to look at patient-clinician interactions from the
Allen, Jennifer
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Evolution of Flightless Ratite Birds [PDF]
, 2018 Birds are well known for their unique (other than bats) ability among vertebrates of flight. Through millions of years of evolution, before they were even classified as such, and for reasons and methods still largely unknown, birds evolved the ability to
Karparis, Abigail
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Shear Power Spectrum Reconstruction using Pseudo-Spectrum Method
, 2010 We develop a pseudo power spectrum technique for measuring the lensing power spectrum from weak lensing surveys in both the full sky and flat sky limits.
Bacon +43 more
core +1 more source