Results 121 to 130 of about 27,933,437 (394)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Study on dynamic characteristics of a rolling agricultural tire (Improvement of running condition)

open access: yesNihon Kikai Gakkai ronbunshu, 2014
When agricultural machines are operated on pavements, the vibration and noise caused by the interaction between the tire lugs and the road surface are inevitable.
Katsuhide FUJITA   +2 more
doaj   +1 more source

The 2dF Galaxy Redshift Survey: power-spectrum analysis of the final data set and cosmological implications [PDF]

open access: yes, 2005
We present a power-spectrum analysis of the final 2dF Galaxy Redshift Survey (2dFGRS), employing a direct Fourier method. The sample used comprises 221 414 galaxies with measured redshifts.
S. Cole   +31 more
semanticscholar   +1 more source

Features in the primordial power spectrum? A frequentist analysis

open access: yes, 2010
Features in the primordial power spectrum have been suggested as an explanation for glitches in the angular power spectrum of temperature anisotropies measured by the WMAP satellite.
Hamann, Jan   +2 more
core   +3 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Proposal of a Ball Burnishing Method with Forced Rotation

open access: yesTribology Online, 2011
In this report, a new ball burnishing process in which the ball is forced to be rotated is proposed. A ball rolling friction test apparatus in which the rotational speed of the ball can be controlled was developed. Controlling the rotational speed of the
Masaru Futamura   +3 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Singular spectrum analysis combined with ARMAX model for structural damage detection

open access: yes, 2017
Time series analysis is being used popularly in structural health monitoring mainly because of its output‐only and non‐modal approach. Generally, the damage features are extracted either from the coefficients or the prediction errors of the time series ...
K. Lakshmi, A. Rao, N. Gopalakrishnan
semanticscholar   +1 more source

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