Results 81 to 90 of about 4,487,534 (292)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Impact of Sensing Range on Spatial-Temporal Opportunity [PDF]
, 2013 In this paper, we study the impact of secondary user (SU) sensing range on spectrum access opportunity in cognitive radio networks. We first derive a closed-form ex- pression of spectrum access opportunity by taking into ac- count the random variations ...
Li, X., Yun, Z., Zhang, X.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An analysis of the vector meson spectrum from lattice QCD
, 2003 We re-analyse meson sector data from the CP-PACS collaboration's dynamical simulations. Our analysis uses several different approaches, and compares the standard naive linear fit with the Adelaide Anzatz.
Allton +4 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
International Journal of Preventive Medicine, 2018 Background: Reference citation analysis and reference publication year can help to demonstrate the historical context of a research field. Therefore, this study aimed to determine the most important historical publications regarding depression prevention.
Ehsan Geraei +2 more
doaj +1 more source
IEEE Access, 2020 Muscle fatigue is required to be assessed in real-time to maintain the best physical condition, especially for sports and rehabilitation areas. In recent years, numerous studies proposed muscle fatigue estimation methods with non-invasive surface ...
Inyeol Yun +3 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Arquivos Brasileiros de Cardiologia, 2007 FUNDAMENTO: Através de mapeamento espectral-(ME) endocárdico em ritmo sinusal, observam-se dois tipos de miocárdio atrial: o compacto de espectro liso e o fibrilar de espectro segmentado ("Ninho de FA" [NFA]).
José Carlos Pachón Mateos +8 more
doaj +1 more source
ppbar enhancement in B and J/Psi decay
, 2006 The near-threshold enhancement in the ppbar invariant mass spectrum from the B^+ -> K^+ ppbar decay reported recently by the BaBar Collaboration is studied within the J\"ulich NNbar model.
A. Sibirtsev +3 more
core +1 more source