Results 81 to 90 of about 24,640,884 (293)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Measurement and modelling of spectrum occupancy [PDF]
Based on the conception of spectrum sharing, cognitive Radio as a promising technology for optimizing utilization of the radio spectrum has emerged to revolutionize the next generation wireless communications industry.
Wang, Zhe
core
Volume 6, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1010/thumbnail ...
Spectrum Contributors,
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Drawing Tower In-Line Fabrication and the Spectrum Analysis of Sampled Fiber Grating
Sampled fiber grating is a special superstructure fiber Bragg grating with a wide range of applications in many fields. In this work, based on drawing tower in-line fabrication system, a new preparation method of the sampled fiber grating is proposed and
Yu Zheng +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Singular Spectrum Analysis: Methodology and Comparison [PDF]
In recent years Singular Spectrum Analysis (SSA), used as a powerful technique in time series analysis, has been developed and applied to many practical problems. In this paper, the performance of the SSA technique has been considered by applying it to a
Hassani, Hossein
core
Background: The subjective limitations of neurobehavioral assessment cause a high misdiagnosis rate for disorders of consciousness (DoC). The purpose of this study was to identify the DoC level based on an analysis of multi-dimensional
Yanhua Shi +7 more
doaj +1 more source

