Results 151 to 160 of about 37,610 (289)
Structure of the boson missing-mass spectrum
Previously, the authors described a possible threefold structure of the boson missing-mass spectrum of the process pi /sup -/+p to X/sup - /+p (see Progr. Theor. Phys., vol. 47, 1974, 1972). New data have since been obtained and the present note examines
Namiki, M, Ohba, I
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Reflections on Ijtihad and Moderate Islam
My remarks focus on two central themes addressed in the preceding debate: moderate Muslim and ijtihad. Although my assignment requires me to engage the five illustrious interlocutors, I have chosen to refer to salient aspects of their statements ...
Louay Safi
doaj
Inclusive Education aims to improve the presence, participation and learning of all students. From this perspective, this article focuses on the learning of mathematics, for which it was analyzed how dialogical communicative acts impact the argumentation of mathematics of students with Autism Spectrum Disorder (ASD) during the development of ...
openaire +1 more source
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Essential spectrum and Weyl asymptotics for discrete Laplacians
In this paper, we investigate spectral properties of discrete Laplacians. Our study is based on the Hardy inequality and the use of super-harmonic functions. We recover and improve lower bounds for the bottom of the spectrum and of the essential spectrum.
BONNEFONT, Michel, GOLENIA, Sylvain
core
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source

