Results 81 to 90 of about 5,578,954 (386)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Neuromyelitis optica spectrum disorder

Advances in Clinical Neuroscience & Rehabilitation, 2017
Over the past 13 years neuromyelitis optica spectrum disorder (NMOSD) has emerged as a discrete form of demyelinating disease of the central nervous system in which antibodies against a water channel found in high concentration on astrocytes are ...
Simon Broadley, Elham Khalili, Saman Heshmat, Laura Clarke   +3 more
doaj   +1 more source

Epilepsy: A Multifaced Spectrum Disorder

Behavioral Sciences, 2023
Epilepsy is one of the most widespread chronic conditions, affecting about 50 million people worldwide [...]
Luigi Vetri, Michele Roccella, Lucia Parisi, Daniela Smirni, Carola Costanza, Marco Carotenuto, Maurizio Elia   +6 more
doaj   +1 more source

Universal subgap optical conductivity in quasi-one-dimensional Peierls systems [PDF]

, 1993
Quasi-one-dimensional Peierls systems with quantum and thermal lattice fluctuations can be modeled by a Dirac-type equation with a Gaussian-correlated off-diagonal disorder.
A. A. Ovchinnikov, A. J. Heeger, C. Weisbuch, D. Berner, F. H. Long, G. Grüner, G. Leising, H. J. Fischbeck, H. Takayama, H. Wagner, I. M. Lifshits, J. M. Williams, J. Rammer, John W. Wilkins, K. Carneiro, Kihong Kim, L. Degiorgi, M. J. Rice, P. A. Lee, P. Brüesch, R. H. McKenzie, R. H. McKenzie, R. P. McCall, Ross H. McKenzie, S. A. Brazovskii   +24 more
core   +3 more sources

Neuromyelitis optica spectrum disorders [PDF]

Clinical Medicine, 2019
Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon antibody-mediated disease of the central nervous system. Long segments of spinal cord inflammation (myelitis), severe optic neuritis, and/or bouts of intractable vomiting and hiccoughs (area postrema syndrome) are classic presentations of the disease and may alert the clinician to the ...
Saif Huda, Dan Whittam, Maneesh Bhojak, Jayne Chamberlain, Carmel Noonan, Anu Jacob, Rachel Kneen   +6 more
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The Role of Psychological Resilience in Reducing Stress and its Impact on Adaptation for Families of Children with Autism Spectrum Disorder

Zanco Journal of Humanity Sciences
The study focuses on analyzing the challenges facing families of individuals with autism disorder and their psychological resilience. A questionnaire was conducted on a random sample of 120 families in Iraq that include individuals with autism disorder.
Osama Farouk Mustafa, Israa Naeem Hamdan   +1 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Expressive language abilities of boys with idiopathic autism spectrum disorder and boys with fragile X syndrome + autism spectrum disorder: Cross-context comparisons

Autism and Developmental Language Impairments, 2020
Background and aims Understanding the unique expressive language profiles of children with phenotypically similar, but distinct neurodevelopmental disorders, such as idiopathic autism spectrum disorder and fragile X syndrome with a co-diagnosis of autism
Elizabeth Hilvert, Audra Sterling, Eileen Haebig, Laura Friedman   +3 more
doaj   +1 more source

Wavepacket Dynamics in One-Dimensional System with Long-Range Correlated Disorder

, 2017
We numerically investigate dynamical property in the one-dimensional tight-binding model with long-range correlated disorder having power spectrum $1/f^\alpha$ ($\alpha:$spectrum exponent) generated by Fourier filtering method.
Yamada, Hiroaki S.
core   +2 more sources