Results 111 to 120 of about 3,255,573 (367)

Hydrodynamics of Binary Fluid Mixtures - An Augmented Multiparticle Collison Dynamics Approach

, 2018
The Multiparticle Collision Dynamics technique (MPC) for hydrodynamics simulations is generalized to binary fluid mixtures and multiphase flows, by coupling the particle-based fluid dynamics to a Ginzburg-Landau free-energy functional for phase ...
Eisenstecken, Thomas, Gompper, Gerhard, Hornung, Raphael, Winkler, Roland G.   +3 more
core   +1 more source

Irony Comprehension in High-Function Autism Spectrum Disorders: A Meta-Analysis

Communication Sciences & Disorders, 2023
Objectives: Irony is a type of figurative language that conveys the opposite meaning of what is said, and it is known to cause difficulty for those with autism spectrum disorder because the expression of spoken language and the non-verbal context are inconsistent.
Younjung Choi, Kyungrang Baik, Young Tae Kim   +2 more
openaire   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Stable charge density wave phase in a 1T-TiSe$_2$ monolayer

, 2017
Charge density wave (CDW) phases are symmetry-reduced states of matter in which a periodic modulation of the electronic charge frequently leads to drastic changes of the electronic spectrum, including the emergence of energy gaps.
Hsu, Chuang-Han, Lin, Hsin, Pereira, Vitor M., Singh, Bahadur, Tsai, Wei-Feng   +4 more
core   +1 more source

Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease‐causing mutations in patients with SSADH deficiency

Human Mutation, 2003
Succinate semialdehyde dehydrogenase (SSADH; ALDH5A1) deficiency, a rare metabolic disorder that disrupts the normal degradation of GABA, gives rise to a highly heterogeneous neurological phenotype ranging from mild to very severe.
S. Akaboshi, B. Hogema, A. Novelletto, P. Malaspina, G. Salomons, G. Maropoulos, C. Jakobs, M. Grompe, K. Gibson   +8 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Blurred magnitude homology of functional connectome for ASD diagnosis

Frontiers in Psychiatry
Autism spectrum disorder (ASD) is one of the most common neurodevelopmental disorders. Existing studies show that adults with ASD may experience accelerated or altered neurocognitive aging.
Alexander Kachura, Vsevolod Chernyshev, Oleg Kachan, Egor Levchenko   +3 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A Knowledge-Driven Framework Discovers Brain ACtivation-Transition-Spectrum (ACTS) Features for Parkinson’s Disease

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Dopaminergic treatment has proved effective to Parkinson’s disease (PD), but the conventional treatment assessment is human-administered and prone to intra- and inter-assessor variability. In this paper, we propose a knowledge-driven framework and
Jiewei Lu, Jin Wang, Yuanyuan Cheng, Zhilin Shu, Yue Wang, Xinyuan Zhang, Zhizhong Zhu, Yang Yu, Jialing Wu, Jianda Han, Ningbo Yu   +10 more
doaj   +1 more source

The Numerical Sausage [PDF]

, 1994
The renormalization group equation describing the evolution of the metric of the non linear sigma models poses some nice mathematical problems involving functional analysis, differential geometry and numerical analysis.
Belardinelli, Lorenzo, Onofri, Enrico
core