Reply to "Ultrasound-guided sub transverse interligamentary (STIL) block versus erector spinae plane (ESP) block for postoperative analgesia in patients undergoing modified radical mastectomy (MRM)". [PDF]
Anand N +5 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Gastronomic paradigm shifts revisited: from culinary abstraction to a post-digital integrative cuisine. [PDF]
Del Moral RG.
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
16th Biennial Symposium on Arts & Technology Exhibitions and Workshops [PDF]
Ammerman Center for Arts & Technology, Connecticut College
core +1 more source
Remnant cholesterol in chronic obstructive pulmonary disease-phenotypes and pharmacotherapy matter. [PDF]
Hao J, Gu X.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Analysis of the anti-scalping mechanism of hospital appointment registration based on Bayesian theory. [PDF]
Zou X, Wang L, Sun J, Guo S, Huang Y.
europepmc +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
May-Thurner Syndrome and Its Possible Influence on Pulmonary Embolism Severity: A Case Report. [PDF]
Nabhan E +3 more
europepmc +1 more source

