Results 51 to 60 of about 20,219 (263)
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Chance and Improbability [PDF]
, 2011 ‘Chance and Improbability’ is an article featuring in a peer-reviewed online journal, Flusser Studies. It focuses on the role of the improbable or unexpected in relation to art practice and discusses the impact of these concepts, drawing on the work of ...
O'Riley, Tim
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FELIX A full acceptance detector at the LHC [PDF]
, 1998 The FELIX collaboration has proposed the construction of a full acceptance detector for the LHC, to be located at Intersection Region 4, and to be commissioned concurrently with the LHC.
Avati, V., Eggert, K., Taylor, C.
core +2 more sources
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Seeing the light – finding the poetic content of design objects [PDF]
, 2015 This paper presents the process and initial results of a research through design project attempting to understand the poetic qualities of design objects.
Duncan, Trevor +3 more
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Categorisation of visualisation methods to support the design of Human-Computer Interaction systems [PDF]
, 2016 During the design of Human-Computer Interaction (HCI) systems, the creation of visual artefacts forms an important part of design. On one hand producing a visual artefact has a number of advantages: it helps designers to externalise their thought and ...
Alcock, Jeffrey R. +3 more
core +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Sense and symbolic objects: Strategic sensemaking through design [PDF]
, 2012 This paper reports on an ongoing investigation into one aspect of the design thinking phenomenon, namely the use of designed artifacts — sketches, renderings, graphics, models and prototypes — as symbolic objects in strategy making and implementation. It
Stevens, John
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