Results 41 to 50 of about 3,100,396 (344)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Pragmatic Language Difficulties in Children with Specific Language Impairment – A Systematic Review

Journal of Child Language Acquisition and Development, 2021
Specific Language Impairment (SLI) is a developmental disorder wherein a child fails to acquire age-appropriate linguistic skills. The study attempted a systematic review of articles pertaining to pragmatics in children with SLI in the last decade.
Swapna Narayanan, Kavya Vijayan, Prashanth Prabhu P., Mekhala V. G., Animesh Barman   +4 more
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Anonymity In Cyberspace: Judicial and Legislative Regulations [PDF]

, 2013
Historically, the scope of constitutional protections for fundamental rights has evolved to keep pace with new social norms and new technology. Internet speech is on the rise. The First Amendment protects an individual’s right to speak anonymously, but
Qasir, Sophia
core   +1 more source

Speech and language therapy versus placebo or no intervention for speech problems in Parkinson's disease [PDF]

, 2012
Parkinson's disease patients commonly suffer from speech and vocal problems including dysarthric speech, reduced loudness and loss of articulation. These symptoms increase in frequency and intensity with progression of the disease).
Brady, Marian C, Clarke, Carl E, Deane, Katherine, Herd, Clare P, Sackley, Catherine M, Smith, Christina H, Tomlinson, Claire L   +6 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Hearing aid selection, fitting, verification, and validation: audiology practice in India and Australia

The Egyptian Journal of Otolaryngology
Background Verification and validation of hearing aids are linked to several elements of the evidence-based practice (EBP) approach for selecting and fitting hearing aids.
Prajeesh Thomas, Saravanan Palani, Kruthika Shankar   +2 more
doaj   +1 more source

A Brief Report on Telerehabilitation During COVID-19 Outbreak at a Tertiary Care Center in Kerala, India [PDF]

Iranian Rehabilitation Journal, 2023
The unanticipated lockdown following the COVID-19 outbreak significantly impacted the field of rehabilitation, compelling the professionals to switch to tele-mode to continue providing their service without interruption.
Vrinda R, Preethy Susan Reni, Suja K Kunnath, Vinitha Mary George   +3 more
doaj  

What Helps Transformers Recognize Conversational Structure? Importance of Context, Punctuation, and Labels in Dialog Act Recognition

Transactions of the Association for Computational Linguistics, 2021
Dialog acts can be interpreted as the atomic units of a conversation, more fine-grained than utterances, characterized by a specific communicative function.
Piotr Żelasko, Raghavendra Pappagari, Najim Dehak   +2 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source