Results 41 to 50 of about 74,156 (264)
Directive Illocutionary Act Produce by the Characters in Cruella Movie
This study aims to determine the types of the directive act and its function found in the American Disney movie Cruella, released in 2021. The study was conducted with the observation method and analyzed using quantitative and qualitative methods.
Ni Kadek Nia Febriola +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
CLASSIFICATION AND WAYS OFEXPRESSION OF SUGGESTIVES
The article focuses on different classifications of speech acts called suggestives in the framework of speech acts theory on the basis of modern English literature.
Alexandra Michailovna Kochergan
doaj
This Research Entitled “An Analysis Of Direct And Indirect Speech Acts Performed By Main Character In The Movie Revenant Script”. This research was a descriptive analysis that discusses direct and indirect speech acts in movie script entitled ‘The ...
Fyngky Oktadistio +2 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Arabic terms usage problems in Islamic Movement Community are interested to be explored by the researchers because the linguistic situation in Islamic Movement Community is enough unique if it is compared with the linguistic situation in another ...
Retno Purnama Irawati
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
DIRECTIVE SPEECH ACTS REALIZATION OF INDONESIAN EFL TEACHER
This research examines the types and functions of directive speech act performed by an Indonesian EFL teacher in one senior high school in Kuningan, Indonesia. This study uses qualitative method.
Cucu Suhartini, Yulianti Wulansari
doaj
Discourse, Statement and Speech Act
Being a component of socio-cultural interaction discourse constitutes a sophisticated cohesion of language form, meaning and performance, i.e. communicative event or act.
Elena Alexandrovna Krasina
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source

