Results 41 to 50 of about 3,005,955 (300)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Speech act of the characters in disney movie encanto
, 2023 This study aims to analyze and explain how the speech act conveyed in Encanto movie directly or indirectly using John R. Searle theory. The writer uses qualitative analysis method in conducting this research.The researcher found thirty data of ...
Moh. supardi,, Yoga eka permana .
core
wav2vec2-based Speech Rating System for Children with Speech Sound Disorder
, 2022 The computational resources were provided by Aalto ScienceIT. This work was supported by NordForsk through the funding to Technology-enhanced foreign and second-language learning of Nordic languages, project number 103893.Speaking is a fundamental way of
Getman, Yaroslav +8 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
ANALISIS PRAGMATIK PADA FUNGSI TINDAK TUTUR DALAM FILM KARYA WALT DISNEY
Prasasti: Journal of Linguistics, 2019 Film is one communication media to deliver message. This study investigates speech act in the film by using pragmatics approarch. Children film is chosen since children indirectly get new vocabulary in the form of word, phrase, or sentence through film ...
Sukasih Ratna Widayanti +1 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
CLASSIFICATION AND WAYS OFEXPRESSION OF SUGGESTIVES
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The article focuses on different classifications of speech acts called suggestives in the framework of speech acts theory on the basis of modern English literature.
Alexandra Michailovna Kochergan
doaj
Utilization Of The Direct And Indirect Speech Act Of Assertion By The Sentence Types
الأستاذ, 2018 Tackling any text, e.g. political one, without pragmatic theory constitutes a real problem in the communicative act. the need to shed light on distinctive rules concerning the speech act of assertion is crucial. So this study is concerned with how to
Samir Jamal Ibraheem
doaj +1 more source
Directive Illocutionary Act Produce by the Characters in Cruella Movie
Lite: Jurnal Bahasa, Sastra, dan Budaya, 2022 This study aims to determine the types of the directive act and its function found in the American Disney movie Cruella, released in 2021. The study was conducted with the observation method and analyzed using quantitative and qualitative methods.
Ni Kadek Nia Febriola +2 more
doaj +1 more source