Results 41 to 50 of about 74,156 (264)

Directive Illocutionary Act Produce by the Characters in Cruella Movie

open access: yesLite: Jurnal Bahasa, Sastra, dan Budaya, 2022
This study aims to determine the types of the directive act and its function found in the American Disney movie Cruella, released in 2021. The study was conducted with the observation method and analyzed using quantitative and qualitative methods.
Ni Kadek Nia Febriola   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

CLASSIFICATION AND WAYS OFEXPRESSION OF SUGGESTIVES

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2013
The article focuses on different classifications of speech acts called suggestives in the framework of speech acts theory on the basis of modern English literature.
Alexandra Michailovna Kochergan
doaj  

AN ANALYSIS OF DIRECT AND INDIRECT SPEECH ACTS PERFORMED BY MAIN CHARACTER IN THE MOVIE REVENANT SCRIPT

open access: yesJournal of English Education and Teaching, 2018
This Research Entitled “An Analysis Of Direct And Indirect Speech Acts Performed By Main Character In The Movie Revenant Script”. This research was a descriptive analysis that discusses direct and indirect speech acts in movie script entitled ‘The ...
Fyngky Oktadistio   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

PENGGUNAAN ISTILAH BERBAHASA ARAB PADA KOMUNITAS PERGERAKAN ISLAM DI KOTA SEMARANG: TINJAUAN SOSIOPRAGMATIK

open access: yesAl-Ta'rib, 2014
The Arabic terms usage problems in Islamic Movement Community are interested to be explored by the researchers because the linguistic situation in Islamic Movement Community is enough unique if it is compared with the linguistic situation in another ...
Retno Purnama Irawati
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

DIRECTIVE SPEECH ACTS REALIZATION OF INDONESIAN EFL TEACHER

open access: yesEnglish Review: Journal of English Education, 2015
This research examines the types and functions of directive speech act performed by an Indonesian EFL teacher in one senior high school in Kuningan, Indonesia. This study uses qualitative method.
Cucu Suhartini, Yulianti Wulansari
doaj  

Discourse, Statement and Speech Act

open access: yesRussian journal of linguistics: Vestnik RUDN, 2016
Being a component of socio-cultural interaction discourse constitutes a sophisticated cohesion of language form, meaning and performance, i.e. communicative event or act.
Elena Alexandrovna Krasina
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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