A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Throat and acoustic paired speech dataset for deep learning-based speech enhancement. [PDF]
Kim Y, Song Y, Chung Y.
europepmc +1 more source
Sound Localization and Speech Enhancement Algorithm Based on Dual-Microphone. [PDF]
Tao T +8 more
europepmc +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
C-EMDNet: A Nonlinear Morphological Deep Framework for Robust Speech Enhancement. [PDF]
Khaldi K +4 more
europepmc +1 more source
Self-attending RNN for Speech Enhancement to Improve Cross-corpus Generalization. [PDF]
Pandey A, Wang D.
europepmc +1 more source
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
Speech enhancement method based on multi-domain fusion and neural architecture search
In order to further improve the self-learning and noise reduction ability of speech enhancement model, a speech enhancement method based on multi-domain fusion and neural architecture search was proposed.The multi-spatial domain mapping and fusion ...
Rui ZHANG, Pengyun ZHANG, Chaoli SUN
doaj +2 more sources
Multichannel speech enhancement for automatic speech recognition: a literature review. [PDF]
Zaland Z +6 more
europepmc +1 more source

