Results 61 to 70 of about 30,269 (257)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Implementation of Hybrid Speech Dereverberation Systems and Proposing Dual Microphone Farsi Database in Order to Evaluating Enhancement Systems [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2013
In various applications, such as speech recognition and automatic teleconferencing, the recorded speech signals may be corrupted by both noise and reverberation. Reverberation causes a noticeable change in speech intelligibility and quality.
Farhad Faghani, Hamid Reza Abutalebi
doaj  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Speech Enhancement Based on Constrained Low-rank Sparse Matrix Decomposition Integrated with Temporal Continuity Regularisation

open access: yesArchives of Acoustics, 2019
Speech enhancement in strong noise condition is a challenging problem. Low-rank and sparse matrix decomposition (LSMD) theory has been applied to speech enhancement recently and good performance was obtained.
Chengli SUN, Conglin YUAN
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

An In-Depth Review of Speech Enhancement Algorithms: Classifications, Underlying Principles, Challenges, and Emerging Trends

open access: yesAlgorithms
Speech enhancement aims to improve speech quality and intelligibility in noisy environments and is important in applications such as hearing aids, mobile communications and automatic speech recognition (ASR).
Nisreen Talib Abdulhusein   +1 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Speaker adaptation using codebook integrated deep neural networks for speech enhancement [PDF]

open access: yesJASA Express Letters
Deep neural network (DNN) based speech enhancement techniques have shown superior performance compared to the traditional speech enhancement approaches in handling nonstationary noise.
B Chidambar, D. Hanumanth Rao Naidu
doaj   +1 more source

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