Results 81 to 90 of about 30,269 (257)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Efficacy of virtual reality pure-tone audiometry in training of hearing test for audiologist

Heliyon
Background and objectives: The immersive virtual reality (VR) simulator is advantageous because it is cost-effective, realistic, can be controlled directly by the user, and can be integrated into education and training in otorhinolaryngology. The present
Chanbeom Kwak, Jinsook Kim, Hyunsook Jang, Woojae Han, Young Joon Seo   +4 more
doaj   +1 more source

Speech Enhancement Network Based on Parallel Multi-Attention [PDF]

Jisuanji gongcheng
Regarding the issue of the frequency-domain enhancement of speech affected by interference, a speech enhancement network based on a parallel multi-attention mechanism and an encoding and decoding structure, known as PMAN, is proposed.
ZHANG Chi, WANG Zhong, JIANG Tianhao, XIE Kangmin
doaj   +1 more source

Enhancing Neural Speech Embeddings for Generative Speech Models

2024 Asia Pacific Signal and Information Processing Association Annual Summit and Conference (APSIPA ASC)
We explore a speech enhancement framework where neural speech embeddings, derived from pre-trained self-supervised learning (SSL) models applied to noisy signals, are used as inputs to a neural vocoder to generate the corresponding clean speech. The primary innovation lies in enhancing these latent neural embeddings to mitigate distortions caused by ...
Kim, Doyeon, Song, Yanjue, Madhu, Nilesh, Kang, Hong-Goo   +3 more
openaire   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Multichannel speech enhancement algorithm based on hybrid reverberation model

Tongxin xuebao
To solve the speech enhancement problem in reverberation and noise scenarios, a new speech enhancement model was constructed integrating multichannel linear prediction model and spatial coherence model, and then a multichannel speech enhancement ...
XIE Yuan, ZOU Tao, SUN Weijun, XIE Shengli   +3 more
doaj  

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Time-Domain Speech Enhancement for Robust Automatic Speech Recognition. [PDF]

Interspeech, 2023
Yang Y, Pandey A, Wang D.
europepmc   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source