Results 131 to 140 of about 1,463,434 (325)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Re-using features of English as a foreign language (EFL) materials for special needs students of the same age group [PDF]

open access: yes, 2006
This paper identifies a lack of age-appropriate literacy software for dyslexic teenagers in Irish classrooms and investigates the features of English as a Foreign Language (EFL) software that could be helpful to dyslexic students.
Greene, Cara N.
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

AI-VoiceTherapy: An Automated Platform for Voice Rehabilitation Using Artificial Intelligence

open access: yesInternational Journal of Computer Engineering and Data Science
AI-VoiceTherapy is a mobile platform that leverages artificial intelligence to democratize access to speech therapy. The system uses OpenAI's Whisper model to automatically detect and analyze speech disorders from voice recordings, including stuttering,
Nisrine Lachguer   +2 more
doaj   +4 more sources

Improving High School Speech Activities on the Basis of Competence-Based Approach

open access: yesФилологический класс, 2012
The article is devoted to renewal of methodical system that ensures the development of senior pupil speech. The author considers the idea of interconnected learning basic kinds of speech activity.
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

SPEECH DEVELOPMENT EXERCISES IN CHILDREN DIAGNOSED WITH DYSLALIA

open access: yes
Dyslalia is a speech disorder characterized by impaired sound pronunciation in children in the absence of organic defects in the auditory and central nervous systems. This scientific thesis analyzes the system of exercises used in the development of speech in children diagnosed with dyslalia, their psycholinguistic foundations, the principles of ...
Makhmudova, O.T., Obloyorova, D.
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

EXERCISES THAT IMPLEMENT AN IDEOGRAPHIC APPROACH TO THE STUDY OF THE NATIVE LANGUAGE

open access: yesФилологический класс, 2018
The article is devoted to the actual methodological problem — the formation of student’s ability to consciously use lexical and grammatical language tools to create statements that accurately reflect reality.
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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