Results 61 to 70 of about 86,691 (269)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Quality of Experience (QoE)-Aware Fast Coding Unit Size Selection for HEVC Intra-Prediction
Future Internet, 2019 The exorbitant increase in the computational complexity of modern video coding standards, such as High Efficiency Video Coding (HEVC), is a compelling challenge for resource-constrained consumer electronic devices.
Buddhiprabha Erabadda +3 more
doaj +1 more source
Information Bottleneck: Theory and Applications in Deep Learning
Entropy, 2020 The information bottleneck (IB) framework, proposed in [...]
Bernhard C. Geiger, Gernot Kubin
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Distribution and Timing of Verbal Backchannels in Conversational Speech: A Quantitative Study
LanguagesThis paper explores backchannels, short listener responses such as “mhm”, which play an important role in managing turn-taking and grounding in spontaneous conversation.
Michael Paierl +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
HyperKon: A Self-Supervised Contrastive Network for Hyperspectral Image Analysis
Remote SensingThe use of a pretrained image classification model (trained on cats and dogs, for example) as a perceptual loss function for hyperspectral super-resolution and pansharpening tasks is surprisingly effective.
Daniel La’ah Ayuba +3 more
doaj +1 more source
3D video bit rate adaptation decision taking using ambient illumination context
Engineering Science and Technology, an International Journal, 2014 3-Dimensional (3D) video adaptation decision taking is an open field in which not many researchers have carried out investigations yet compared to 3D video display, coding, etc.
G. Nur Yilmaz +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source