Results 11 to 20 of about 36,429 (223)

Detecting Dysfluencies in Stuttering Therapy Using wav2vec 2.0 [PDF]

open access: yes, 2022
Stuttering is a varied speech disorder that harms an individual's communication ability. Persons who stutter (PWS) often use speech therapy to cope with their condition. Improving speech recognition systems for people with such non-typical speech or tracking the effectiveness of speech therapy would require systems that can detect dysfluencies while at
arxiv   +1 more source

AI-Based Automated Speech Therapy Tools for persons with Speech Sound Disorders: A Systematic Literature Review [PDF]

open access: yes, 2022
This paper presents a systematic literature review of published studies on AI-based automated speech therapy tools for persons with speech sound disorders (SSD). The COVID-19 pandemic has initiated the requirement for automated speech therapy tools for persons with SSD making speech therapy accessible and affordable.
arxiv   +1 more source

HAIDA: Biometric technological therapy tools for neurorehabilitation of Cognitive Impairment [PDF]

open access: yesIn: Masia L., Micera S., Akay M., Pons J. (eds) Converging Clinical and Engineering Research on Neurorehabilitation III. ICNR 2018. Biosystems & Biorobotics, vol 21. Springer, Cham, 2022
Dementia, and specially Alzheimer s disease (AD) and Mild Cognitive Impairment (MCI) are one of the most important diseases suffered by elderly population. Music therapy is one of the most widely used non-pharmacological treatment in the field of cognitive impairments, given that music influences their mood, behavior, the decrease of anxiety, as well ...
arxiv   +1 more source

KSoF: The Kassel State of Fluency Dataset -- A Therapy Centered Dataset of Stuttering [PDF]

open access: yesarXiv, 2022
Stuttering is a complex speech disorder that negatively affects an individual's ability to communicate effectively. Persons who stutter (PWS) often suffer considerably under the condition and seek help through therapy. Fluency shaping is a therapy approach where PWSs learn to modify their speech to help them to overcome their stutter.
arxiv  

STAN: A stuttering therapy analysis helper [PDF]

open access: yesDemo presented at 2021 IEEE Spoken Language Technology Workshop (SLT), 2021
Stuttering is a complex speech disorder identified by repeti-tions, prolongations of sounds, syllables or words and blockswhile speaking. Specific stuttering behaviour differs strongly,thus needing personalized therapy. Therapy sessions requirea high level of concentration by the therapist.
arxiv  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Teaching Turn-Taking Skills to Children with Autism using a Parrot-Like Robot [PDF]

open access: yesarXiv, 2021
Robot Assisted Therapy is a new paradigm in many therapies such as the therapy of children with autism spectrum disorder. In this paper we present the use of a parrot-like robot as an assistive tool in turn taking therapy. The therapy is designed in the form of a card game between a child with autism and a therapist or the robot.
arxiv  

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