Results 121 to 130 of about 3,700,119 (305)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
ActuatorsIn this study, a novel composite speed controller combining a sliding-mode speed controller with a disturbance observer is proposed for the vector-controlled synchronous reluctance motor (SynRM) drive system.
Yong-Chao Liu
doaj +1 more source
Gas turbine engine fuel control [PDF]
, 1973 A variable orifice system is described that is responsive to compressor inlet pressure and temperature, compressor discharge pressure and rotational speed of a gas-turbine engine.
Gold, H. S.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hybrid fuzzy- proportionl integral derivative controller (F-PID-C) for control of speed brushless direct curren motor (BLDCM) [PDF]
, 2017 Hybrid Fuzzy proportional-integral-derivative (PID) controllers (F-PID-C) is designed and analyzed for controlling speed of brushless DC (BLDC) motor. A simulation investigation of the controller for controlling the speed of BLDC motors is performed to ...
Farag A. M., Elkarghali
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Electro-chemical grinding [PDF]
, 1972 Electro-chemical grinding technique has rotation speed control, constant feed rates, and contour control. Hypersonic engine parts of nickel alloys can be almost 100% machined, keeping tool pressure at virtual zero.
Feagans, P. L.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
机车电传动Relevant enterprises in China and abroad are striving to make technological breakthroughs in developing platforms that integrate vehicle control and signal systems to optimize train operation across multiple aspects, including operational control ...
WANG Xiangyang +5 more
doaj