Results 81 to 90 of about 6,283,447 (256)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Economic Effectiveness of Operation and Utilization of Large Container Carriers

open access: yesCommunications, 2016
This paper deals with operational effectiveness of large container carriers transporting standardized transportation units. The calculation is related to costs per one TEU transported. What is a very important factor in maritime transport is the vessel's
Jaromir Siroky, Hana Vohankova
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Dual-channel representation learning with wind speed correction factor for enhanced wind power forecasting

open access: yesEnergy and AI
Wind power forecasting (WPF) accuracy is fundamentally constrained by two critical challenges. First, the high-order nonlinear relationship between wind speed (WS) and power (WP) substantially amplifies errors inherent in numerical weather prediction ...
Yanbo Chen   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Research on forging forming force in the composite technology of cross wedge rolling (CWR) and forging for universal joint fork

open access: yesMetalurgija, 2019
In this paper,the forging process of universal joint fork of automobile transmission shaft is simulated and the change of forming force of die forging is studied on the basis of the blank produced by cross wedge rolling (CWR).
J. Y. Xu, B. S. Sun, N. Li
doaj  

Numerical Analysis of Pulling Speed Impact on Optical Fiber Coating in a Pressurized Applicator

open access: yesNTU Journal of Engineering and Technology
Optical fibers manufacturing has become one of the most important and promising processes in different industrial, medical and telecommunications fields.
Nameer A. Mahmood, Omar Dh. Jumaah
doaj   +1 more source

HS2 Phase One: London to West Midlands Historic Environment Digital Archive

open access: yes
Parent collection for Phase One of the High Speed 2 railway line (London to West Midlands)
High Speed Two Ltd.
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Performance Evaluation of Horizontal Axis Wind Turbine Torque and Mechanical Power Generation Affected by the Number of Blade

open access: yesMATEC Web of Conferences, 2016
This paper presents the evaluation of horizontal axis wind turbine torque and mechanical power generation and its relation to the number of blades at a given wind speed. The relationship of wind turbine rotational frequency, tip speed, minimum wind speed,
Tan Rodney H. G., Teow Matthew Y. W.
doaj   +1 more source

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